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26 projets européens trouvés

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 TERMINÉ 

European Prevention of Alzheimer’s Dementia Consortium (EPAD)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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 40

 TERMINÉ 

DIabetes REsearCh on patient sTratification (DIRECT)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2019,

The overarching aims of the DIRECT consortium, consisting of 20 leading academic groups in diabetes and 5 EFPIA companies, are to identify biomarkers that address current bottlenecks in diabetes drug development and to develop a stratified medicines approach to treatment of type 2 diabetes with either existing or novel therapies.There is heterogeneity in who develops diabetes, the rate at which th ...
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 27

 TERMINÉ 
"Aging populations, rising costs and sustainable delivery of high-quality care are increasingly common concerns in all EU countries. PACE aims to perform comparative effectiveness research concerning palliative care in long term care facilities (LTCFs) in Europe. While a growing number of older people will require palliative care in institutionalized settings, palliative care has only recently beg ...
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 13

 TERMINÉ 
"Glioblastomas (GBMs) are malignant brain tumours and among the most aggressive human cancers. GBMs patients have an extremely poor survival rate due to a complete absence of adequate therapies capable of efficiently targeting GBM cells inside the brain. Recently, we demonstrated that GBM cells release pro-tumoural extracellular vesicles (EVs) into the bloodstream, which emerged as important inter ...
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 1

 TERMINÉ 
Concept and aim: 20 million fans attend top division football games each week and many more watch on TV. Our social innovation is to attract people to lifestyle change through the personal connection and loyalty to the club they support. Our aim is to use this social innovation to change physical activity and sedentary behaviour, specially targeting low-SES groups, and men as well as women. EuroFI ...
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 13

 TERMINÉ 
"Knee Osteoarthritis (KOA) is the most common chronic musculoskeletal disorder, currently affecting over 8 million people within the EU, for which currently no cure is available. Adverse biomechanics, affected through some of the major health issues of our time (ageing, obesity, sedentary lifestyle) lie at the heart of the disease.The research theme of the KNEEMO ITN is “towards targeted and tailo ...
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 8

 TERMINÉ 
Conduct Disorder (CD) and Oppositional Defiant Disorder with symptoms of Conduct Disorder (which is included among the abbreviation “CD” throughout the proposal) has a highly negative impact for the affected individual as well as for families and society. Although the number of females exhibiting serious aggressive behaviours is growing, the majority of studies on aetiology and treatment of CD hav ...
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 19

 TERMINÉ 

From Patient Data to Clinical Diagnosis in Neurodegenerative Diseases (PredictND)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Dementia is a growing health problem with enormous costs to society: the costs currently equal 1% of the global gross-domestic product and a three-fold increase to 115 million dementia cases is expected by 2050. Addressing this grave human and economic challenge requires efficient solutions that do not exist yet: tools to detect and diagnose persons at an early phase, and interventions for delayin ...
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 10

 TERMINÉ 
Vitamin D deficiency has significant implications for human health and impacts on healthy growth and development and successful aging. Fundamental knowledge gaps are barriers to implementing a safe and effective public health strategy to prevent vitamin D deficiency and optimize status. ODIN will provide the evidence to prevent vitamin D deficiency in Europe and improve nutrition and public health ...
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 32

 TERMINÉ 

Long-term effects of early nutrition on later health (EARLYNUTRITION)

Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,

Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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 40

 TERMINÉ 
"Our first goal is to develop a new tool to determine brain activity with a high temporal (< 1 msec) and spatial (about 2 mm) resolution with the focus on motor control. High density EEG (up to 256 electrodes) will be used for EEG source localization. Advanced force-controlled robot manipulators will be used to impose continuous force perturbations to the joints. Advanced closed-loop system identi ...
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 3

 TERMINÉ 

MOBILISING THE POTENTIAL OF ACTIVE AGEING IN EUROPE (MOPACT)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

The starting point for MOPACT is the ambitious goals set by Horizon 2020 and the European Innovation Partnership Pilot Project on Active and Healthy Ageing (EIPAHA). Our response is ambitious too: we aim to provide the research and practical evidence upon which Europe can make longevity an asset for social and economic development. MOPACT will create a high quality, multi-disciplinary critical mas ...
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 32

 TERMINÉ 
Problem:The need for cost effective health systems in Europe is imperative in the context of an increasing demand for health care by growing numbers of elderly people and a shrinking working force. Many health care systems are changing and looking for mechanisms to ensure, measure and improve the quality of care. On the other hand it is unclear which models of care delivery are the most cost-effec ...
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 8

 TERMINÉ 
MiRacle focuses on the development of a therapeutic formulation for the treatment of head and neck cancer. Head and neck cancer contributes to approximately 5% of all cancers in the Western world. Unfortunately the majority of H&N cancer patients present with advanced stages of disease. These patients frequently develop locoregional recurrences, distant metastasis and/or second primary tumors resu ...
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 9

 TERMINÉ 
Description OraMod project: Helping clinicians predict oral cavity cancer reoccurrenceGenomic markers and computer models can predict the reoccurance of oral cavity cancer. But these innovative diagnostic technologies are currently stuck in labs and are not being used by clinicians in hospitals. The EU-funded project OraMod, led by the Un ...
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 9

 TERMINÉ 
Indications exist that close contact with nature brings benefits to human health and well-being. The proposed work will investigate the interconnections between exposure to natural outdoor environments, in both rural and urban settings, and better human health and well-being in the North West, South and East of Europe. The project will explore the underlying mechanisms at work (stress reduction/re ...
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 13

 TERMINÉ 
Europe is facing a rapidly growing threat from Type 2 diabetes mellitus (T2D), which is undoubtedly associated with an unhealthy diet and a more sedentary lifestyle. Evidence is accumulating that gestational diabetes mellitus (GDM) may be playing a role in this process. Thus it provides a significant opportunity for preventing future T2D. Not only is GDM prevalence on the rise, but intrauterine ex ...
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 18

 TERMINÉ 

Accurate EEG source localisation using patient tailored head models (PTS4DEEG)

Date du début: 1 juin 2014, Date de fin: 31 mai 2015,

EEG records electric potential differences from electrodes attached to the human skin. Although multi-channel EEG can be used to localize its underlying sources, clinical application of this technique in, e.g. epilepsy and stroke monitoring, requires long preparation time to acquire electrode position and head shape and is also hampered by the poor knowledge of in vivo skull conductivity.In the ER ...
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 2

 TERMINÉ 
Recent epidemiological studies suggest that cancer risk after exposures with doses comparable to the dose limits for occupationally exposed workers may be larger than assumed by ICRP in the derivation of these limits. The value of cancer risk from such exposures and its dependence on tissue, radiation type and individual factors is largely unknown. The innovative approach proposed here combines ep ...
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 23

 TERMINÉ 

The COMET (Core Outcome Measures in Effectiveness Trials) Initiative (COMET)

Date du début: 1 oct. 2012, Date de fin: 31 déc. 2014,

"Clinical trialists often struggle when trying to choose the outcomes to measure which would be of most use to the patients, practitioners and policy makers who will use their research to help them make decisions. These difficulties are passed on to those producing and reading systematic reviews, many of whom have experienced the frustration of finding that the original researchers either did not ...
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 11

 TERMINÉ 
EURO IMPACT aims to develop a multi-disciplinary, multi-professional and intersectorial educational and research training network aimed at monitoring and improving palliative care in Europe. Palliative care is less than optimal in many developed countries and some patients suffer from severe symptoms. While international research on palliative care has begun to develop over the past decades, it ha ...
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 9

 TERMINÉ 
Objective The ToyBox proposal addresses KBBE-2009-2-1-03 - Behavioural models for prevention of obesity, with a particular focus on children. It will primary aim to influence children’s behaviours and prevent obesity in early childhood. Strategy The proposal will identify key behaviours related to early childhood obesity and their determinants and evaluate behavioural models and educational strate ...
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 18

 TERMINÉ 
The prevalence of obesity has increased steadily for the past several decades. The great public health burden of overweight and obesity requires effective intervention programs targeting energy balance behaviours (e.g. active transport, tv viewing, soft drink and snacking consumption). However, up to now the efforts to prevent overweight had disappointing effects. To better inform future systemati ...
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 4

 TERMINÉ 
EuroGentest is an FP6 European network for the harmonization of genetic testing and for the further improvement of quality in genetic services across Europe.This proposal is to support EuroGentest2, a Coordination Action that will cover the different aspects of quality assurance of genetic practice and has all the ingredients to fulfil the needs. EuroGentest2 will be concerned with setting the tar ...
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 22

 TERMINÉ 
Hypertrophic cardiomyopathy (HCM), characterised by left ventricular hypertrophy and myocyte disarray, is by far the most common cardiac single gene disorder. With a prevalence of 1:500, HCM is predicted to affect approximately one million people within the EU. HCM represents an important clinical problem, being the principal cause of sudden death in young adults, and a valuable opportunity to use ...
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 8

 TERMINÉ 

EuropeaN Energy balance Research to prevent excessive weight Gain among Youth (ENERGY)

Date du début: 1 févr. 2009, Date de fin: 31 juil. 2012,

"Objective: The ENERGY proposal addresses HEALTH-2007-3.3-1: Promoting healthy behaviour in children and adolescents. It will be specifically focussed on promoting health behaviours that contribute to prevention of overweight and obesity among children and adolescents. Strategy: The project will use a multidisciplinary analysis of determinants and intervention schemes on extrinsic and intrinsic f ...
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 16