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 TERMINÉ 
Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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 27

 TERMINÉ 
"SOLUTIONS will deliver a conceptual framework for the evidence-based development of environmental and water policies. This will integrate innovative chemical and effect-based monitoring tools with a full set of exposure, effect and risk models and assessment options. Uniquely, SOLUTIONS taps (i) expertise of leading European scientists of major FP6/FP7 projects on chemicals in the water cycle, (i ...
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 41

 TERMINÉ 

Health and Environment-wide Associations based on Large population Surveys (HEALS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools th ...
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 37

 TERMINÉ 
Background:Hyperinsulinaemic hypoglycaemia (HH) is a potentially lethal disease caused by over functioning beta cells derived from the pancreatic islets of Langerhans. Lethal HH and brain damage is a problem especially in infants with congenital HH. Current therapeutic approaches are associated with severe side effects/morbidity (diabetes, exocrine pancreas insufficiency etc.) considered acceptabl ...
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 17

 TERMINÉ 
This project aims to unite global efforts to target the highly druggable class of enzymes called cyclic nucleotide phosphodiesterases (PDEs) in the fight for neglected parasitic diseases (NPD). It will establish a drug discovery platform, PDE4NPD, that combines phenotypic screening with efficient target-centric drug discovery, including target validation, various strategies for compound screening, ...
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 11

 TERMINÉ 

ASCENT - Advanced Solid Cycles with Efficient Novel Technologies (ASCENT)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

"ASCENT will provide a robust proof-of-concept of three related high temperature processes; each will lead to a step-change in efficiency of carbon removal in three types of pre-combustion capture, producing the hydrogen needed for highly efficient low-carbon power production. The project brings together five small and medium enterprises preparing to launch these concepts with the support of leadi ...
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 18

 TERMINÉ 
Concentrating Solar Thermal Energy encompasses Solar Thermal Electricity (STE), Solar Fuels, Solar Process Heat and Solar Desalination that are called to play a major role in attaining energy sustainability in our modern societies due to their unique features: 1) Solar energy offers the highest renewable energy potential to our planet; 2) STE can provide dispatchable power in a technically and eco ...
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 42

 TERMINÉ 

Clearing Clutter Bit by Bit (SQUIRREL)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Clutter in an open world is a challenge for many aspects of robotic systems, especially for autonomous robots deployed in unstructured domestic settings, affecting navigation, manipulation, vision, human robot interaction and planning.SQUIRREL addresses these issues by actively controlling clutter and incrementally learning to extend the robot's capabilities while doing so. We term this the B3 (bi ...
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 10

 TERMINÉ 

European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,

ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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 48

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 
A new EU 7th Framework Programme project, “LEANWIND” (Logistic Efficiencies And Naval architecture for Wind Installations with Novel Developments) seeks to apply lean principles to the offshore wind farm project lifecycle. The primary LEANWIND objective is to provide cost reductions across the offshore wind farm lifecycle and supply chain through the application of lean principles and the developm ...
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 32

 TERMINÉ 

Kinetics for Drug Discovery (K4DD) (K4DD)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

There is mounting evidence that the often ignored kinetic aspects of the interaction between a drug and its target are highly relevant for clinical success. This ignorance may be one of the reasons for the high attrition rates in drug discovery, as it has been analyzed that many recently marketed drugs had indeed improved kinetic profiles. This hindsight knowledge needs to be converted into data-d ...
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 21

 TERMINÉ 
Organ transplantation has emerged as the “gold standard” therapy for end-stage organ failure. Incomplete control of chronic allograft injury but also the adverse effects of long-term immunosuppression (IS) continue to challenge the long-term success of transplantation. The paradigm is shifting from increasing “net”-IS by novel drugs to the concept of minimizing long-term IS as early as possible. H ...
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 17

 TERMINÉ 
Preventing immunological rejection of transplanted organs without the need for long-term use of pharmacological immunosuppression is a primary objective in transplantation medicine. Reducing the need for immunosuppression would dramatically improve the outcome for transplant recipients and reduce health costs for society. The means to achieve this goal has not been realised with pharmacological or ...
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 16

 TERMINÉ 
Nanomedicine offers capability to significantly change the course of treatment for life-threatening diseases. Many of the most significant current therapeutic targets, to be viable in practice, require the efficient crossing of at least one biological barrier. However, the efficient and controlled crossing of the undamaged barrier is difficult. The range of small molecules that can successfully do ...
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 9

 TERMINÉ 

CI-NERGY Smart cities with sustainable energy systems (CI-NERGY)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

The CI-NERGY Marie Curie Initial Training Network (ITN) aims to train young scientists to develop urban decision making and operational optimisation software tools to minimise non-renewable energy use in cities. The training will be carried out by a close collaboration of six of the best academic research centres and four leading industrial companies from the energy and software technology sector ...
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 11

 TERMINÉ 

European-wide field trials for residential fuel cell micro-CHP (ENE.FIELD)

Date du début: 1 sept. 2012, Date de fin: 31 août 2017,

ene.field will deploy up to 1,000 residential fuel cell Combined Heat and Power (micro-CHP) installations, across 11 key Member States. It represents a step change in the volume of fuel cell micro-CHP (micro FC-CHP) deployment in Europe and a meaningful step towards commercialisation of the technology.The programme brings together 9 mature European micro FC-CHP manufacturers into a common analysis ...
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 29

 TERMINÉ 
The vision of SelSus is to create a new paradigm for highly effective, self-healing production resources and systems to maximise their performance over longer life times through highly targeted and timely repair, renovation and up-grading. These next generation machines, fixtures and tools will embed extended sensory capabilities and smart materials combined with advanced ICT for self-diagnosis en ...
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 16

 TERMINÉ 

"Codeine Use, Misuse and Dependence" (CODEMISUSED)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

"Contemporary research has underscored the need for ‘increased pharmaco-vigilence’ around codeine dispensing as the most commonly consumed opiate worldwide. Codeine represents an interesting quandary in terms of its regulated status, with individuals varying in their metabolism of codeine, estimation of safe dosages, and abuse potential. Within user trajectories of codeine use, a variety of sub gr ...
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 6

 TERMINÉ 

"Graphene Layers: Production, Characterization and Integration" (GLADIATOR)

Date du début: 1 nov. 2013, Date de fin: 30 avr. 2017,

"GLADIATOR (Graphene Layers: Production, Characterization and Integration) will enable the scalable production of cheaper, higher quality and larger area graphene sheets. The project will achieve this by optimizing the performance of CVD graphene (using doping), by increasing the throughput and size of CVD batch reactors, and by improving the process by which graphene is transferred for the CVD ca ...
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 16

 TERMINÉ 
eDIGIREGION is a unique collaborative project that brings together a balanced blend of complimentary and experienced partners from four diverse regions. The sixteen (16) people involved in formulating this proposal are senior executives and decision makers in their respective organisations. These partners have embarked upon, are committed to, and have already demonstrated the power of transnationa ...
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 16

 TERMINÉ 

VPH Dementia Research Enabled by IT (VPH-DARE@IT)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

The DementiA Research Enabled by IT project responds to the European Parliament's 2011 resolution for a European Initiative on Alzheimer's disease and other dementias, and the EU Year of the Brain 2014 Initiative. It delivers the first patient-specific predictive models for early differential diagnosis of dementias and their evolution. Its mechanistic/phenomenological models of the ageing brain ac ...
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 22

 TERMINÉ 

DARPin Targeted Magnetic Hyperthermic Therapy for Glioblastoma (DARTRIX)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,

"DARTRIX, ‘DARPin Targeted RX (therapy)’ is a multidisciplinary collaborative project that will develop high-affinity protein scaffolds to create a new generation of targeted therapeutics for the treatment of glioblastoma. There is great need; glioblastoma is virtually incurable and most patients die within 12 months of diagnosis. DARPins are small, non-immunoglobulin human protein scaffolds that ...
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 8

 TERMINÉ 

New operational steps towards an alliance of European research fleets (EUROFLEETS2)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

EUROFLEETS2 is the enhancement of EUROFLEETS1, with the aim of developing a new pan-European distributed infrastructure with common strategic vision and coordinated access to Research Vessels (RVs) and marine equipment. EUROFLEETS2 will furthermore undertake specific actions to consolidate research fleets’ organization, methodology and tools through operational initiatives (like virtual fleets) le ...
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 32

 TERMINÉ 

Automotive Fuel Cell Stack Cluster Initiative for Europe II (Auto-Stack CORE)

Date du début: 1 mai 2013, Date de fin: 28 févr. 2017,

Several automotive OEMs have announced plans for the commercialization of fuel cell vehicles from 2014/15. Industrial partnerships such as H2-Mobility in Germany, the UK or Hydrogen Highway in Scandinavia are working to establish the required initial H2- infrastructure While this is a clear signal for the functional readiness of fuel cell technology in automotive application, durability, efficienc ...
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 16

 TERMINÉ 
The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke.Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so it ...
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 38

 TERMINÉ 

Europeana Sounds

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,

The Europeana Sounds is Europeana's 'missing' fifth domain aggregator, joining APEX (Archives), EUscreen (television), the Europeana Film Gateway (film) and TEL (libraries). It will increase the opportunities for access to and creative re-use of Europeana's audio and audio-related content and will build a sustainable best practice network of stakeholders in the content value chain to aggregate, en ...
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 24

 TERMINÉ 
The target of the Smartonics project is the development of Pilot lines that will combine smart technologies with smart nanomaterials for the precision synthesis of Organic Electronic (OE) devices.The Smartonics objectives are:1.Development of smart Nanomaterials for OEs (polymer & small molecule films, plasmonic NPs and super-barriers) by process and computational modeling optimization.2.Developme ...
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 19

 TERMINÉ 

Energy efficiency Management for Vehicles and Machines (EMVEM)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

In view of reducing the ecological footprint of machines and vehicles, effective and efficient analysis techniques and adequate measurement technologies are required to produce world-leading products with a high energy-efficiency, without compromising functionality/safety/performance/etc. Combined with the increasing trend towards virtual design and prototyping, to reduce costs and development tim ...
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 13

 TERMINÉ 

Dengue research Framework for Resisting Epidemics in Europe (DENFREE)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

"WHO estimates that one of the main consequences of global warming will be an increased burden of vector-borne diseases. Among these, dengue appears to be particularly problematic, with tens of millions of cases of dengue fever estimated to occur annually, including up to 500,000 cases of the life-threatening dengue hemorrhagic fever/dengue shock syndrome. In recent years, the global burden of den ...
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 15

 TERMINÉ 

Membrane Protein Nanocrystallography (NanoMem)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

Modern structural biology builds upon synergies between lab-bench scale science on the one hand and large scale research infrastructure on the other. NanoMem recognises the transformative opportunities that are created by current X-ray source and detector developments to impact strongly on membrane protein structure, a challenging sub-field of structural biology. We will exploit synchrotron based ...
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 11

 TERMINÉ 

Epigenetic regulation of economically important plant traits (EPITRAITS)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

The mission of EpiTRAITS is to train young researchers in epigenetic gene regulation and flowering in the model plant Arabidopsis thaliana and the crop plants maize (Zea mays) and barley (Hordeum vulgare). Epigenetic gene regulation confers stability of gene expression patterns through cell divisions while allowing changes in expression in response to environmental or developmental cues. Although ...
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 13

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

Preparing NUGENIA for HORIZON2020 (NUGENIA-PLUS)

Date du début: 1 sept. 2013, Date de fin: 30 sept. 2016,

Preparing NUGENIA for HORIZON 2020The objective of the NUGENIA+ project is to support the NUGENIA Association in its role to coordinate and integrate European research on safety of the Gen II and III nuclear installations in order to better ensure their safe long term operation, integrating private and public efforts, and initiating international collaboration that will create added value in its a ...
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 52

 TERMINÉ 
"The core concept of Accelerated Metallurgy is to deliver an integrated pilot-scale facility for the combinatorial synthesis and testing of many thousands of unexplored alloy formulations. This facility would be the first of its kind in the world and would represent a significant advance for metallurgy. The novel technology that enables this HTT facility is based on automated, direct laser deposit ...
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 34

 TERMINÉ 
Parasites exact a devastating toll on health and economic productivity, infecting man and also domestic livestock. Drugs used to combat parasitic diseases are deficient in many ways and new, better drugs are needed to establish sustainable means to combat diseases caused by protozoan parasites that include malaria, trypanosomiasis and leishmaniasis in man, and coccidiosis among others in animals. ...
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 12

 TERMINÉ 
The All-Electric Aircraft is a major target for the next generation of aircraft to lower consumption of non-propulsive power and thus fuel burn. To eliminate hydraulic circuits, pumps and reservoirs, Electro Mechanical Actuators (EMA) are mandatory but now need to meet cost, reliability and weight requirements from the airframers.ACTUATION2015 aims to develop and validate a common set of standard ...
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 56

 TERMINÉ 

Graphene-Based Revolutions in ICT And Beyond (GRAPHENE)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2016,

This Flagship aims to take graphene and related layered materials from a state of raw potential to a point where they can revolutionize multiple industries – from flexible, wearable and transparent electronics, to new energy applications and novel functional composites.Our main scientific and technological objectives in the different tiers of the value chain are to develop material technologies fo ...
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 154

 TERMINÉ 

Rapid deployable kits as seeds for self-recovery (S(P)EEDKITS)

Date du début: 1 mars 2012, Date de fin: 29 févr. 2016,

Humanitarian organisations like the Red Cross have sleeping emergency response units (ERU), which start acting immediately after disaster strikes. Each ERU has a specific function, e.g. medical care, sanitation, energy provision, or water supply.Current equipment solutions will be scanned and bottlenecks with respect to large volumes and/or heavy weight will be identified. Then, novel materials an ...
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 16

 TERMINÉ 

Smart production of Microsystems based on laminated polymer films (SMARTLAM)

Date du début: 1 oct. 2012, Date de fin: 31 janv. 2016,

Today´s fabrication methods for micro devices can require expensive tooling and long turnaround times, making empirical, performance-based modifications to the design expensive and time consuming. These methods also are limited in their flexibility, so that complex devices, that incorporate on-board valves, separation media, membranes, and recirculating pumps, cannot be developed and adapted witho ...
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 9