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 TERMINÉ 

Applied Public-Private Research enabling OsteoArthritis Clinical Headway (APPROACH)

Date du début: 1 juin 2015, Date de fin: 30 nov. 2020,

The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensi ...
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 25

 TERMINÉ 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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 44

 TERMINÉ 

Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery (ULTRA-DD)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

ULTRA-DD (Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery) will be an European-wide, highly collaborative and inclusive consortium, to validate new targets for drug discovery by (1) generating high quality research tools, with an emphasis on chemical probes; (2) generating the chemical probes in the most cost-effective manner, using structure-guided methods and harne ...
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 10

 TERMINÉ 

Translating neuroimaging findings from research into clinical practice (PSYSCAN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

Abstract 9Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standard ...
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 24

 TERMINÉ 

European Gram Negative Antibacterial Engine (ENABLE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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 42

 TERMINÉ 

European Prevention of Alzheimer’s Dementia Consortium (EPAD)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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 40

 TERMINÉ 

Functional Role of the HLA-DR15 Haplotype in Multiple Sclerosis (HLA-DR15 in MS)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Multiple sclerosis (MS) is a prototypic CD4+ T cell-mediated autoimmune disease that damages the central nervous system. MS affects young adults and women twice as often as men. Neurological deficits cause substantial disability at an early age with high socioeconomic impact.Both a complex genetic trait and environmental factors are involved in MS etiology. Similar to other autoimmune diseases it ...
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 2

 TERMINÉ 

Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood (CANCER-ID)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Blood-based biomarkers such as Circulating Tumor Cells (CTCs), circulating free tumor DNA (cfDNA) and microRNAs (miRNAs) have the potential to improve the development of personalized medicines for cancer patients. This is of particular importance when biopsies of the primary tumor or metastases are not accessible (e.g. at early disease stages or in minimal residual disease) or possible and the ass ...
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 34

 TERMINÉ 

The History of Human Freedom and Dignity in Western Civilization (HHFDWC)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The ETN has two aims: to a) train ESRs; b) investigate the The History of Human Freedom and Dignity in Western Civilization. a) The ETN will establish an innovative training programme which allows the ESRs to obtain specialist knowledge of a specific research topic and to obtain transferable skills enabling the students to apply their knowledge in non-academic institutions, e.g. dealing with socia ...
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 6

 TERMINÉ 

Advanced strategies for substitution of critical raw materials in photovoltaics (STARCELL)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

STARCELL proposes the substitution of CRM’s in thin film PV by the development and demonstration of a cost effective solution based on kesterite CZTS (Cu2ZnSn(S,Se)4) materials. Kesterites are only formed by elements abundant in the earth crust with low toxicity offering a secure supply chain and minimizing recycling costs and risks, and are compatible with massive sustainable deployment of electr ...
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 15

 TERMINÉ 

The Dynamics of Solidarity on Madagascar: An Ethnography of Political Conflicts and Appeasement Strategies in the Context of a Pronounced Consens Norm (DySoMa)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,

The aim of this anthropological research project is to improve understanding of the peace-making processes operating in the ongoing Malagasy political crisis. A dispute in 2009 over the Malagasy presidency, the most powerful political position on the island, marked the beginning of a particularly difficult period. At first tensions were limited to the national political level, but the situation ra ...
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 1

 TERMINÉ 

FROM TRADITION TO INNOVATION IN TEACHER TRAINING INSTITUTIONS

Date du début: 15 oct. 2016, Date de fin: 14 oct. 2019,

Although Latin American society has gained greater access to education at all levels, government officials in education, schoolteachers, trainers and researchers are calling into question the ability of their higher education institutions (HEIs) to address education professionals' needs. Typically, such groups criticize the bureaucracy of HEI training programmes, their failure to address practice ...
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 21

 TERMINÉ 

New Methods and Applications for Forecast Evaluation (Forecasting)

Date du début: 1 juil. 2014, Date de fin: 30 juin 2019,

Forecasting is a fundamental tool in Economics, Statistics, Business and other sciences. Judging whether forecasts are good and robust is of great importance since forecasts are used everyday to guide policymakers' and practitioners' decisions. The proposal aims at addressing four important issues that researchers encounter in practice.A first issue is how to assess whether forecasts are optimal i ...
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 2

 TERMINÉ 

Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strateg (ACTION)

Date du début: 1 juin 2014, Date de fin: 31 mai 2019,

Aggression inflicts a huge personal, psychological and financial burden on affected individuals, their relatives, and society at large. Despite large scientific, preventive, and treatment investments, no decrease in aggressive behavior is seen. This calls for a shift to new approaches. By capitalising on comprehensive longitudinal cohorts, recent advances in genetic, biological, epidemiological, a ...
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 12

 TERMINÉ 

ECOPOTENTIAL: IMPROVING FUTURE ECOSYSTEM BENEFITS THROUGH EARTH OBSERVATIONS (ECOPOTENTIAL)

Date du début: 1 juin 2015, Date de fin: 31 mai 2019,

Terrestrial and marine ecosystems provide essential services to human societies. Anthropogenic pressures, however, cause serious threat to ecosystems, leading to habitat degradation, increased risk of collapse and loss of ecosystem services. Knowledge-based conservation, management and restoration policies are needed to improve ecosystem benefits in face of increasing pressures. ECOPOTENTIAL makes ...
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 47

 TERMINÉ 

Labor Market Risk and Skill Diversity: Implications for Efficiency, Policy, and Estimation (RISK AND DIVERSITY)

Date du début: 1 mai 2014, Date de fin: 30 avr. 2019,

Labor market risk and skill diversity are central features of the labor market. Arguably, employment risk is one of the biggest sources of uncertainty most individuals face in their life time. Likewise, exploiting the synergies and complementarities between differentially skilled workers is amongst the greatest challenges to firms' hiring decisions. The objective is to analyze the efficiency prope ...
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 2

 TERMINÉ 

Unravelling the unicellular prehistory of metazoans with functional analyses and single-cell genomics (PREMETAZOANEVOLUTION)

Date du début: 1 mai 2014, Date de fin: 30 avr. 2019,

"How multicellular animals (metazoans) emerged from their single-celled ancestor remains a long-standing evolutionary question. Recent genome data has shown that the unicellular ancestor of metazoans already had a complex gene repertoire for genes involved in cell adhesion, cell signaling and transcriptional regulation, including integrins, cadherins, T-box genes, and protein tyrosine kinases. Thu ...
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 2

 TERMINÉ 

Virtual Academy for Professionals in the field of Education and Training of Vision Impaired People

Date du début: 1 oct. 2016, Date de fin: 31 mars 2019,

This project main goal is to influence and conduct the modernization of the education and training system used in organizations working in the field of visual impairment directly focusing on their professional bodies, bridging a deficiency of available specific training in this area in many of the participating countries, while, at the same time, promoting the exchange of experience and know-how b ...
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 8

 TERMINÉ 

RepliCable and InnovaTive Future Efficient Districts and cities (CITYFIED)

Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,

"CITyFiED project aims to develop a replicable, systemic and integrated strategy to adapt European cities and urban ecosystems into the smart city of the future, focusing on reducing the energy demand and GHG emissions and increasing the use of renewable energy sources by developing and implementing innovative technologies and methodologies for building renovation, smart grid and district heating ...
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 18

 TERMINÉ 

Advancing the European Multilingual Experience (ATHEME)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,

"The project Advancing The European Multilingual Experience (AThEME) takes an integrated approach towards the study of multilingualism in Europe by incorporating and combining linguistic, cognitive and sociological perspectives; by studying multilingualism in Europe at three different levels of societal magnitude, viz. the individual multilingual citizen, the multilingual group, and the multilingu ...
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 18

 TERMINÉ 

Soft and Small: Acoustic Transducers Inspired by Nature (SASATIN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

"The use of sound by humanity is ubiquitous. We utilise sound across a far greater range than we can hear for numerous extremely beneficial tasks. In Nature many animals have evolved ears, many of which are sensitive to sounds beyond human audibility. This includes an enormous variety of insects whose miniature ears detect sound to communicate, to detect their prey, or to avoid their own predators ...
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 1

 TERMINÉ 

Next Generation Driving Behaviour Models (NG-DBM)

Date du début: 1 févr. 2015, Date de fin: 31 janv. 2019,

"Microscopic traffic simulation tools which replicate individual driver decisions and combine them to deduce network conditions are popular tools for evaluating transport planning and management options. An essential component of such tools is a set of mathematical models of driver behaviour, including but not limited to longitudinal movement models, lateral movement models, and route choice model ...
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 1

 TERMINÉ 

UPF Fellows (UPFellows)

Date du début: 1 mai 2013, Date de fin: 31 janv. 2019,

The UPFellows program promoted by Universitat Pompeu Fabra - UPF aims to offer career development opportunities to outstanding junior postdoctoral researchers of any nationality. They will join one of the most unique and dynamic research environments in Europe, where they will be able to advance in their research and further develop their professional skills with a career development plan guided b ...
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 1

 TERMINÉ 

Metal catalysis in biological habitats: New strategies for optical bio-sensing and targeted therapy (METBIOCAT)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

"This proposal aims at the discovery of robust transition-metal catalyzed transformations that can take place in aqueous media and cellular lysates, and are susceptible of being exported to living cells. Specifically, we will exploit the special coordination and activation ability of different metal complexes towards pi-systems to induce chemo-selective reactions of designed, abiotic, unsaturated ...
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 1

 TERMINÉ 

Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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 30

 TERMINÉ 

"The role of consciousness in adaptive behavior: A combined empirical, computational and robot based approach" (CDAC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

"Understanding the nature of consciousness is one of the grand outstanding scientific challenges and two of its features stand out: consciousness is defined as the construction of one coherent scene but this scene is experienced with a delay relative to the action of the agent and not necessarily the cause of actions and thoughts. Did evolution render solutions to the challenge of survival that in ...
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 2

 TERMINÉ 

Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease: Comparative Effectiveness Research of Existing Technologies (DISCHARGE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Coronary artery disease (CAD) is the leading cause of death in high-income countries. Invasive coronary angiography (ICA) is the reference standard for the diagnosis of CAD and allows immediate therapy. However, only 40% of patients undergoing ICA actually have obstructive CAD and ICA has relatively rare but considerable risks. Coronary computed tomography (CT) is the most accurate diagnostic test ...
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 38

 TERMINÉ 

Treatment of late onset bacterial sepsis caused by vancomycin susceptible bacteria in neonates and infants aged under three months (NEOVANC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Vancomycin is the critically important antibiotic to treat neonatal Late Onset Sepsis (LOS) due to Gram positive bacteria in neonates, including Coagulase Negative Staphylococci (CoNS) and Staphylococcus aureus. These organisms also create biofilms which are extremely resistant to antibiotics. The increased incidence of LOS due to bacteria such as CoNS and MRSA in NICUs has led to a marked increas ...
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 14

 TERMINÉ 

How citizens try to influence politics and why. International comparisons of movement and party politics (POLPART)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

Protests in ‘new’ democracies about ‘stolen elections’, demonstrations in ‘old’ democracies against austerity measures, occupied squares all over the world against inequality and for better governance. Some argue that contentious politics gains importance and party politics declines. Is that so and why would that be? Why is it that some individuals engage in politics while others remain apathetic? ...
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 5

 TERMINÉ 

Intelligent Assessment of Pharmaceutical in the Environment (IPIE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Active pharmaceutical ingredients (APIs) can be released to the natural environment during the manufacturing process, following use by patients or when unused medicines are disposed of. As APIs are biologically active compounds concerns have been raised about the potential effects of APIs in the environment on human and environmental health. Over the past 15 years, a substantial amount of work has ...
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 29

 TERMINÉ 

Wheat and barley Legacy for Breeding Improvement (WHEALBI)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

WHEALBI will combine genomics, genetics and agronomy to improve European wheat and barley production in competitive and sustainable cropping systems. Germplasm representing the species diversity will be selected and characterised in unprecedented detail by next-generation-sequencing. Life history and adaptive traits will be evaluated in both transnational field experiments and a state-of-the-art p ...
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 20

 TERMINÉ 

Biological origins of linguistic constraints (BIOCON)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2018,

The linguistic capacity to express and comprehend an unlimited number of ideas when combining a limited number of elements has only been observed in humans. Nevertheless, research has not fully identified the components of language that make it uniquely human and that allow infants to grasp the complexity of linguistic structure in an apparently effortless manner. Research on comparative cognition ...
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 1

 TERMINÉ 

Neuropathic pain: biomarkers and druggable targets within the endogenous analgesia system (NEUROPAIN)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

Neuropathic pain has a high incidence in Europe and often affects the patient’s emotional balance and quality of life. Recent meta-analyses have shown that conventional analgesic drugs are not sufficiently effective in these patients and are limited by serious side effects. The search for new analgesics is extremely difficult despite identification of several new potential targets and enormous inv ...
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 12

 TERMINÉ 

Língua, Investigação, Desenvolvimento, Oportunidade!

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2018,

Project LIDO - Language, Investigation, Development, Opportunity - seeks to boost the inclusion of the participation of visually impaired people in vocational training and intercultural activities with other European countries - students and staff of the organization. The main objectives are: to encourage the development of the use of a foreign LANGUAGE, INVETIGATE new perspective to Develop bette ...
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 3

 TERMINÉ 

Rozšíření odborných kompetencí žáků v oblasti CNC řízení strojů a inovace školních vzdělávacích programů.

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2018,

...nd these skills during technology training. Within the framework of their professional training they meet Sinumerik and Fanuc systems, which our school owned. The educational stay at United School in Martin will build on these acquired skills and expand on the skills of Heidenhain. Pupils learn about the technical parameters of the system, its operating modes, operation control in manual mode, lea ...
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 2

 TERMINÉ 

Dynamics-aerosol-chemistry-cloud interactions in West Africa (DACCIWA)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

"Massive economic and population growth and urbanisation are expected to lead to a tripling of anthropogenic emissions in southern West Africa (SWA) between 2000 and 2030, the impacts of which on human health, ecosystems, food security and the regional climate are largely unknown. An assessment of these impacts is complicated by (a) a superposition with effects of global climate change, (b) the st ...
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 17

 TERMINÉ 

Sustainable intensive pig and poultry production (PROHEALTH)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

Production diseases compromise health and welfare, generating inefficiencies which impact adversely on profitability, environmental footprint, antibiotic use and product quality.The PROHEALTH project will develop understanding of the multi-factorial dimension of animal pa-thologies linked to the intensification of production and use this to develop, evaluate and disseminate ef-fective control stra ...
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 24

 TERMINÉ 

Advanced T-cell Engineered for Cancer Therapy (ATECT)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

"T-cell engineering strategies for Cancer therapy, either Chimeric Antigen Receptors (CARs) or TCR transfer holds promise to revolutionize cancer treatment. There are, however, considerable barriers to be overcome to take this form of therapy to a format that can benefit all EU citizens with a wide range of common cancers. The aim of this consortium is to exploit advances in T-cell engineering to ...
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 6

 TERMINÉ 

Stratospheric and upper tropospheric processes for better climate predictions (StratoClim)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

StratoClim will produce more reliable projections of climate change and stratospheric ozone by a better understanding and improved representation of key processes in the Upper Troposphere and Stratosphere (UTS). This will be achieved by an integrated approach bridging observations from dedicated field activities, process modelling on all scales, and global modelling with a suite of chemistry clima ...
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 30

 TERMINÉ 

Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, including tolerance, withdrawal and respiratory/circulatory depression. Clonidine is commonly used for sedation in PICU and recom ...
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 10