2 projets européens trouvés
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TERMINÉ
Unravelling paradoxes in regulatory T cell biology: the molecular basis for an mTOR-dependent oscillatory metabolic switch controlling immune tolerance and autoimmunity (menTORingTregs)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,
Our group has been investigating how the nutrient/energy-sensing mammalian target of rapamycin (mTOR)-pathway affects the responsiveness of CD4+CD25+FoxP3+ regulatory T cells (Tregs). We have shown that Tregs have a high metabolic profile associated with the hyperactivation of the mTOR-pathway, which is responsible for the in vitro anergy of these cells. A transient mTOR inhibition with rapamycin, ...
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TERMINÉ
An Open, Ubiquitous and Adaptive Chronic Disease Management Platform for COPD and Renal Insufficiency (CHRONIOUS)
Date du début: 1 févr. 2008, Date de fin: 31 mai 2012,
Description
Health and lifestyle monitoring of people with chronic diseases at a European level. The project developed for example a smart T-shirt to monitor and help the chronically illChronic diseases are the leading causes of death and disability for a large amount of people in most industrialized nations. Chronic diseases have also a ...
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