3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Biophysical study of the coupling between cell proliferation and morphogen gradients (MORPHOGRAD)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2015,
As well as controlling patterning, morphogens such as the Drosophila BMP homolog Decapentaplegic (Dpp) also regulate growth during development, but how they do so remains largely unclear. One privileged hypothesis, called the steepness hypothesis, suggests that cells in a tissue read spatial differences in the morphogen gradient and divide accordingly. However, the host lab recently discovered a n ...
Voir le projet
1
Participant partenaire
TERMINÉ
Characterization of the role of morphogens during growth of the Zebrafish pectoral fin using advanced biophysical tools (MORFING)
Date du début: 1 mars 2010, Date de fin: 29 févr. 2012,
"During development an organ grows to a final size and shape and its cells acquire information about their position and differentiate according to their location. Morphogens play an important role in this process by coordinating growth and patterning of developing tissues. In this project the fellow will fully characterize the growth of the pectoral fin of the Zebrafish, a vertebrate, and study th ...
Voir le projet
1
Participant partenaire
TERMINÉ
Asymmetric endosomes in asymmetric cell division and tumorigenesis (ENDASYM)
Date du début: 1 juin 2009, Date de fin: 31 mai 2011,
"Recent Drosophila reports show that directional Notch signalling during asymmetric cell division is mediated by asymmetric endocytic trafficking. Unpublished data from the host lab showed that directional Notch signalling is initiated by the directed targeting towards the signal-receiving cell of specific endocytic compartments, the Sara endosomes, which carry the receptor Notch and its ligand De ...
Voir le projet