5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Perceptual Awareness in the Reorganizing Brain (Perceptual Awareness)
Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,
"The present project aims at casting light on the neural and cognitive reorganization of visual function following unilateral lesion at various levels of the central visual system such as optic tract, optic radiation, primary visual cortex, extrastriate visual areas. In the first part of the project we will employ behavioural as well as brain imaging methods to study the basic neural mechanisms of ...
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4
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TERMINÉ
Beating Heart
Date du début: 1 sept. 2014, Date de fin: 31 août 2016,
Intravital microscopy (IVM) methods are enjoying an ever broader acceptance as they can be used to gain insight into cell biology in vivo. Unfortunately, most set-ups use window chambers (e.g. cancer) or isolated organs, all highly artificial model systems which are often not compatible with survival imaging. Because of these caveats, imaging in orthotopic locations is always preferable and can th ...
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2
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TERMINÉ
Prediction of cognitive properties of new drug candidates for neurodegenerative diseases in the early clinical development (PHARMA-COG)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2015,
PHARMA-COG aims to develop a new integrated model to accelerate the development of drug cindidates for MS, PKD and AD. The innovation relies on a 'multidimensional matrix' approach, integrating all available and renewed inputs (biomarkers/animal, human models/physiological and pharmcological challenges, Phase 0/1/1b to reduce the attrition rate, to allow an early and pertinent GO/NOGO decision bef ...
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38
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TERMINÉ
A Treatment-Oriented Research Project of NCL Disorders as a Major Cause of Dementia in Childhood (DEM-CHILD)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,
"The DEM-CHILD project focusses on the main cause for childhood dementia in Europe, the neuronal ceroid lipofuscinoses (NCLs). The NCLs are neurodegenerative diseases characterized by dementia, blindness, epilepsy and physical decline leading to an early death of the patients. Since no cure is currently available, these disorders represent a serious social, medical, and economic challenge.To date, ...
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13
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TERMINÉ
GENOMIC AND TRANSCRIPTIONAL ANALYSIS OF GLIOBLASTOMA MICROENVIRONMENTAL CELLULAR SUBSETS USING ANTIBODY MICROARRAYS (Crosstalk in GBMs)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,
The applicant is an experienced researcher with the objective of completing comprehensive training in translational research on Glioblastoma Multiforme (GBM), one of the most common malignant and lethal primary brain tumor of adults, with the final aim of disposing of personalized therapeutic protocols for GBM and cancer patients. The project is based on the finding that human tumors, particularly ...
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