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 EN COURS 
Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
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 21

 EN COURS 
The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they ar ...
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 19

 TERMINÉ 

The artificial pancreas in children aged 1 to 7 years with type 1 diabetes (KidsAP)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2020,

TYPE 1 DIABETES is one of the most COMMON CHRONIC diseases in children with a RAPID increase in number of cases particularly in young children. Type 1 diabetes is associated with LIFE-LONG dependency on insulin administration. POOR glucose control leads to diabetes COMPLICATIONS, e.g. eye, heart, kidney disease, including BRAIN changes in young children. Episodes of VERY LOW glucose levels may be ...
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 14

 TERMINÉ 
Blood-based biomarkers such as Circulating Tumor Cells (CTCs), circulating free tumor DNA (cfDNA) and microRNAs (miRNAs) have the potential to improve the development of personalized medicines for cancer patients. This is of particular importance when biopsies of the primary tumor or metastases are not accessible (e.g. at early disease stages or in minimal residual disease) or possible and the ass ...
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 34

 TERMINÉ 

EUROPLANET 2020 Research Infrastructure (EPN2020-RI)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

The Europlanet 2020 Research Infrastructure (EPN2020-RI) will address key scientific and technological challenges facing modern planetary science by providing open access to state-of-the-art research data, models and facilities across the European Research Area. Its Transnational Access activities will provide access to world-leading laboratory facilities that simulate conditions found on planetar ...
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 35

 TERMINÉ 
Chronic kidney disease (CKD) is an important public health problem worldwide, especially in older people. Indeed, population aging in industrialized countries is accompanied by an increase in the prevalence of CKD and its complications. Although its prevalence and the importance of an early diagnosis to prevent complications such as end-renal stage disease (ESRD), screening programme in Europe are ...
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 11

 TERMINÉ 

Heart OMics in AGEing (HOMAGE)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2019,

As more people survive into old age, the prevalence of heart failure (HF), one of the most common and debilitating diseases in older people, will rise still further. Delaying or preventing HF will have great benefit to those at personal risk, their families, society and the economy. HOMAGE aims to provide a biomarker (BM) approach that will a) help identify i. patients at high risk of developing ...
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 22

 TERMINÉ 

Complex Oscillatory Systems: Modeling and Analysis (COSMOS)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Many natural and artificial systems are often composed of oscillatory elements which, besides evolving according to their own non-trivial internal dynamics, mutually interact. As a result, many temporal and spatial scales are typically present, often accompanied by the spontaneous emergence of collective properties. Altogether, such features make the task of understanding the resulting evolution a ...
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 8

 TERMINÉ 
Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems, which regulate energy balance and behaviour. This has led to hypothesize that developing microbiome-based dietary interventions can be cost-effective measures to prevent diet-related and behavioural diso ...
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 30

 TERMINÉ 
Despite examples of excellent practice, rare disease (RD) research is still mainly fragmented by data and disease types. Individual efforts have little interoperability and almost no systematic connection between detailed clinical and genetic information, biomaterial availability or research/trial datasets. By developing robust mechanisms and standards for linking and exploiting these data, RD-Con ...
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 30

 TERMINÉ 

Contrast by Quadrupole Enhanced Relaxation (CONQUER)

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

The ageing society and demographic change is one of the major challenges which Europe is facing now, and even more so in the future. Mastering this challenge requires radically new diagnostic and therapeutic treatments as key factors in achieving the healthy well-being of European citizens. Molecular imaging (MI) plays a pivotal role in diagnosis, understanding of disease and in the development of ...
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 5

 TERMINÉ 

Bridging Biobanking and Biomedical Research across Europe and Africa (B3Africa)

Date du début: 1 juil. 2015, Date de fin: 30 juin 2018,

B3Africa - Bridging Biobanking and Biomedical Research across Europe and Africa will dramatically improve and facilitate the development of better predictive, preventive and personalized healthcare worldwide. The rapidly evolving African biobanks are an invaluable resource: The African population has the greatest genomic diversity on the planet and represents an incredible resource of information ...
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 12

 TERMINÉ 

Health Care Work Exchange 2016

Date du début: 1 juin 2016, Date de fin: 31 mai 2018,

The “Health Care Work Exchange 2016” project will enable 100 apprentices and students of health care vocational schools from 1 June 2016 to 31 May 2018 to carry out an internship in all countries participating in the ERASMUS+ Mobility Program. Apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical techn ...
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 39

 TERMINÉ 

Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

 TERMINÉ 

Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
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 19

 TERMINÉ 
NanoAthero aims to have demonstration of initial clinical feasibility of nanosystems for targeted imaging and treatment of advanced atherosclerotic disease in humans. The nanosystems are assemblies of following components: nanocarrier, targeting, imaging agent/drug. They have proven safety records, and strong preliminary in vitro and in vivo proofs of efficacy are available. Partners have patented ...
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 17

 TERMINÉ 
The stimulatory NKG2D lymphocyte receptor expressed on natural killer cells and T cells and its tumor-associated ligands enable the immune system to recognize and destroy cancer cells. This role of NKG2D is well recognized and efforts are underway to target NKG2D and its ligands for cancer therapy. However, cancers adopt diverse strategies to safeguard their survival. With advanced human cancers, ...
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 1

 TERMINÉ 

Mars Analogues for Space Exploration (MASE)

Date du début: 13 déc. 2013, Date de fin: 1 janv. 2018,

Assessing the habitability of Mars and detecting life, if it was ever there, depends on knowledge of whether the combined environmental stresses experienced on Mars are compatible with life and whether a record of that life could ever be detected. However, our current ability to make these assessments is hampered by a lack of knowledge of how the combined effect of different environmental stresses ...
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 11

 TERMINÉ 

Single-Port Insulin Infusion for Improved Diabetes Management (SPIDIMAN)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

Existing therapeutic devices for diabetic patients suffer from bulky size, inaccurate measurements and the difficulties of handling two body interfaces. Suboptimal control of blood glucose levels in type 1 or type 2 diabetes mellitus patients results in periods of hypo- and hyperglycaemia leading to severe and life-threatening complications. Exploiting a novel glucose sensor technology, SPIDIMAN a ...
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 9

 TERMINÉ 
Vitamin D deficiency has significant implications for human health and impacts on healthy growth and development and successful aging. Fundamental knowledge gaps are barriers to implementing a safe and effective public health strategy to prevent vitamin D deficiency and optimize status. ODIN will provide the evidence to prevent vitamin D deficiency in Europe and improve nutrition and public health ...
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 32

 TERMINÉ 

Long-term effects of early nutrition on later health (EARLYNUTRITION)

Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,

Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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 40

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2016, Date de fin: 30 sept. 2017,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 
The overall goal of InterConnect is to establish a global network that will facilitate the co-ordination of population research on the interaction between genetic and environmental factors in the aetiology of obesity and diabetes. We aim to establish mechanisms for identification and classification of studies and the data that they hold and create a forum for harmonization of methods as a foundati ...
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 12

 TERMINÉ 

European Research Infrastructure on Highly Pathogenic Agents 2 (ERINHA2)

Date du début: 1 janv. 2016, Date de fin: 30 juin 2017,

ERINHA2 aims to complete the work carried out during the first preparatory phase (PP1) - ERINHA - in order to reach the financial, administrative and technical maturity necessary to complete the establishment of the Research Infrastructre and ensure that the operation phase can begin in 2018. ERINHA2 will therefore finalise the decision to use the status of an association and prepare the necessary ...
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 17

 TERMINÉ 

Health Care Work Exchange 2015

Date du début: 1 juin 2015, Date de fin: 31 mai 2017,

From 1.6.2015 to 31.5.2017 the project “Health Care Work Exchange 2015” will offer 100 apprentices and students of health care vocational schools an opportunity to carry out an internship in all countries participating in ERASMUS+. Foremost apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical technica ...
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 38

 TERMINÉ 
Bacterial infection is the major cause of disability and death in children worldwide. We will use meningococcal disease (MD) as a model to understand genetic factors underlying susceptibility and severity of childhood bacterial infection which will then be applied to other childhood infections. We have established cohorts of patients with MD in Central and Southern Europe (CE,SE), UK and Africa as ...
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 16

 TERMINÉ 
More than 14 million Europeans suffer from heart failure (HF), of which more than 50 % have HF with preserved left ventricular (LV) ejection fraction (EF) (HFPEF, “diastolic heart failure”). HFPEF is the only cardiovascular disease with increasing prevalence and incidence, affecting 10-20% of the elderly and contributing substantially to hospitalizations of elderly HF patients. Currently, no medic ...
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 9

 TERMINÉ 
The ClinicIMPPACT proposal builds upon the successful completion of the IMPPACT project (Grant No. 223877, completed in February 2012) that resulted in the creation of a physiological radio-frequency ablation (RFA) model for liver cancer treatment. This preliminary RFA model has been tested in porcine animal studies with extensive histological workup and in a clinical study using patient data for ...
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 8

 TERMINÉ 

BBMRI - Large Prospective Cohorts (BBMRI-LPC)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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 36

 TERMINÉ 

IMmune MOdulating strategies for treatment of MErkel cell Carcinoma (IMMOMEC)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

"Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer of the skin associated with the recently discovered, common Merkel cell polyomavirus (MCV). With an incidence of 0.44 per 100,000 MCC is a very rare cancer. Notably, however, although MCC is 40 times less common than malignant melanoma, MCC has a dramatically higher mortality rate than melanoma rendering MCC to ...
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 11

 TERMINÉ 
We propose here an exhaustive analysis of the genome, exome, methylome and transcriptome of primary tumours and metastases from patients with colon carcinoma, based on a combination of deep sequencing and chip based techniques. Dependent on their availability, we shall also perform analyses of tumor stem cells, circulating tumor cells, free tumor DNA in serum and xenografts derived from the same p ...
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 22

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2015, Date de fin: 30 sept. 2016,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
Voir le projet

 1

 TERMINÉ 
This proposal aims at collecting and analysing facts and figures in order to assess the current legislation on the therapeutic use of somatic cells, and to bridge it with the research infrastructure capacity building. Although EU has adopted 3 Directives on Tissues and cells between 2004 and 2006 to harmonise the procurement, storage and use of cells for therapeutic use in Europe, countries have i ...
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 9

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

Proof of Concept of Model-based Cardiovascular Prediction (CARDIOPROOF)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

CARDIOPROOF is a proof-of-concept project that consolidates the outcomes of previous VPH projects and checks the applicability and effectiveness of available predictive modelling and simulation tools, validating them in interrelated clinical trials conducted in three European centres of excellence in cardiac treatment (from Germany, Italy and the UK). CARDIOPROOF focuses on patients with aortic va ...
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 10

 TERMINÉ 

European Medicines Research Training Network (EMTRAIN)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2016,

... signed to foster industry/academia mobility and collaboration.The public Consortium is made up of the six pan-European biomedical science (BMS)research infrastructures from the ESFRI roadmap, and the Medizinische Universitaet Wienas managing entity. The six ESFRI-BMS research infrastructures cover a broad spectrum ofcompetences from molecules to humans: structural biology (Instruct), bioinformatic ...
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 32

 TERMINÉ 

Assessing SNOMED CT for Large Scale eHealth Deployments in the EU (ASSESS CT)

Date du début: 1 févr. 2015, Date de fin: 31 juil. 2016,

ASSESS CT will contribute to better semantic interoperability of eHealth services in Europe, in order to optimise care and to minimise harm in delivery of care. In a joint one-year effort, the ASSESS CT consortium will investigate the fitness of the clinical terminology SNOMED CT as a potential standard for EU-wide eHealth deployments, scrutinising clinical, technical, financial, and organisationa ...
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 15

 TERMINÉ 
The Go-Smart project will build a generic open-source software simulation environment for planning of image guided percutaneous Minimally Invasive Cancer Treatment (MICT). MICT includes radiofrequency ablation (RFA), cryoablation, microwave ablation (MW), transarterial chemoembolisation (TACE), brachytherapy (BT), and prospectively, irreversible electroporation (IRE). Beside of TACE each type of M ...
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 9

 TERMINÉ 
The project proposed by the fellow Evelyn Jantscher-Krenn and the scientist in charge, Gernot Desoye, Medical University of Graz, Austria, aims at pinpointing the potential role of Human Milk Oligosaccharides (HMO) as biomarkers in metabolic diseases in pregnancy. HMO are immunomodulatory glycans in breast milk that are also present in the systemic circulation of pregnant women. New evidence detec ...
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 2

 TERMINÉ 

Health Care Work Exchange 2014

Date du début: 1 juin 2014, Date de fin: 31 mai 2016,

From 1.6.2014 to 31.5.2016 the project “Health Care Work Exchange 2014” will offer 100 apprentices and students of health care vocational schools an opportunity to carry out an internship in all countries participating in ERASMUS+. Foremost apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical technica ...
Voir le projet

 27