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5 projets européens trouvés

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 TERMINÉ 

Role of long non coding RNA in muscle differentiation and disease (MUNCODD)

Date du début: 1 juil. 2014, Date de fin: 30 juin 2019,

"The field of interest applies to the study of muscle differentiation and disease. The main objective of this project is to deepen our knowledge on the molecular networks controlling normal muscle differentiation, and to identify their alteration in pathology. The state of art in this field is thoroughly advanced since well-established master regulators (transcriptional factors and miRNAs) have be ...
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 1

 TERMINÉ 

The European non-coding RNA network (RNATRAIN)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"Non-coding RNA (ncRNA) is a new research field in rapid development. It holds the potential to explain many fundamental biological phenomena and there is a vast prospective for the development of ncRNA-derived diagnostic and therapeutic tools. Hence, biotech and pharmaceutical companies are actively looking into this unexplored territory for novel targets. Therefore, there is a substantial and un ...
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 11

 TERMINÉ 
To contribute to the development of vaccines against Shigella and ETEC for children of the developing world, STOPENTERICS will provide novel solutions by imposing a two-fold paradigm switch: (i) to break the dogma of serotype-specificity by inducing a cross-protective immunity (ii) to improve the immunogenicity of Shigella glycoconjugates by using synthetic oligosacharides mimicking the lipopolysa ...
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 20

 TERMINÉ 
"In animals, the formation and growth of new organs cease at the completion of development; in plants, the body is continuously built throughout the plant lifespan. In addition, in plants there is virtually no cell migration due to rigid cell walls: this provides a unique opportunity for dissecting the relations between pattern formation and final organ structure.Plant post-embryonic development t ...
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 1

 TERMINÉ 
"BRAINVECTORS aims devising new gene therapy(GT)-based treatments for Parkinson’s and other neurodegenerative diseases, in substitution of current systemic treatments, by delivering neurotrophic factors (GDNF) into the CNS with new vectors derived from adeno-associated (AAV), canine adenoviruses (CAV) and lentiviruses (LV) with inducible gene expression.Although AAV, CAV and LVV are considered acc ...
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 12