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 TERMINÉ 

Genetic and Phenotypic Modelling of Bacterial Evolution (GENPHENBACT)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,

"The dramatic success of infectious agents comes from their ability to adapt to both immune and pharmaceutical selective pressures. To uncover the dynamics of bacterial adaptation, experimental evolution has been widely used, focusing mostly on organismal fitness. Many of the observation derived from these experiments have been captured by Fisher's Geometric model of Adaptation (FGMA). Despite its ...
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 TERMINÉ 
"Heart failure (HF) affects 14 million people in Europe, and this number is forecast to increase to 30 million by 2020. Early diagnosis of HF is essential for successfully addressing underlying causes. However, initial diagnosis is difficult in many situations so that HF is correctly diagnosed in only half of affected patients. Diastolic HF, for example, that accounts for more than 50% of all HF p ...
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 TERMINÉ 

Machine Learning for Personalized Medicine (MLPM2012)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"Over the last decade, enormous progress has been made on recording the health state of an individual patient down to the molecular level of gene activity and genomic information – even sequencing a patient’s genome for less than 1000 dollars is no longer an unrealistic goal. However, the ultimate hope to use all this information for personalized medicine, that is to tailor medical treatment to th ...
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 TERMINÉ 
Arrhythmias are a major cause of death and disability worldwide and their prevalence is expected to rise with the aging of the population. Recent technological advances have led to the development of new treatments based on radio-frequency (RF) catheter ablation to treat and even cure these conditions. However, challenges in treatment persist. RF ablation is currently performed via direct contact ...
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