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Plus de 40 projets européens trouvés

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 TERMINÉ 

A European Platform for Translational Cancer Research (EUROCANPLATFORM)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2016,

Europe has a number of advantages as regards developing translational cancer research, yet there is no clear European strategy to meet the increasing burden posed by cancer. The FP6 Eurocan+Plus project analysed the barriers underlying the increasing fragmentation of cancer research and stressed the need to improve collaboration between basic/preclinical and comprehensive cancer centres (CCCs), in ...
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 29

 TERMINÉ 

Rational Therapy for Breast Cancer: Individualized Treatment for Difficult-to-Treat Breast Cancer Subtypes (RATHER)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2016,

"Cancer genotyping has identified a number of correlations between mutations in specific genes and responses to targeted anti-cancer drugs, with many mutations occurring in kinases or downstream signaling components. While there are several ongoing large-scale genome re-sequencing studies for the major cancer types, there is no systematic effort to investigate kinase mutations in distinct biologic ...
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 8

 TERMINÉ 

Full Aero-thermal Combustor-Turbine interactiOn Research (FACTOR)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2016,

To achieve lower Specific Fuel Consumption (SFC) and CO2/NOx emissions, modern turbomachineries operate at high velocities and high temperature conditions. The lack of confidence in the prediction of combustor-turbine interactions leads to apply extra safety margins on components design. Therefore, the understanding of combustor-turbine flow field interactions is mandatory to preserve High Pressur ...
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 24

 TERMINÉ 

European collaborative project on Targeted therapy in renal cell cancer: genetic and tumor-related biomarkers for response and toxicity (EuroTARGET)

Date du début: 1 mars 2011, Date de fin: 31 août 2016,

Each year more than 63,000 new cases of kidney cancer are diagnosed in the European Union. Approx. 50% of all patients have metastasized renal cell cancer (mRCC) at presentation or develop metastases during follow-up. 5-year relative survival of mRCC has been extremely poor: between 5 and 10%. In the past few years, so-called targeted therapies that suppress angiogenesis have changed the clinical ...
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 15

 TERMINÉ 

Persistent virus infection as a cause of pathogenic inflammation in type 1 diabetes - an innovative research program of biobanks and expertise (PEVNET)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,

"Type 1 diabetes is caused by an inflammatory process which damage insulin-producing beta-cells in the pancreas. It is one of the most common chronic diseases and its incidence is rapidly increasing. Due to its complications it causes a significant medical and economic burden to European society. A causal association between enterovirus and type 1 diabetes has become more and more likely. The aim ...
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 14

 TERMINÉ 

Epigenetics towards systems biology (EPIGENESYS)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2016,

The ‘EpiGeneSys’ Network of Excellence aims to enable European epigenetics research to enter the arena of systems biology, a new step forward with major implications for human health. Many diseases, not explained solely by gene mutation, have rather been associated with epigenetic disorders. Following the identification of key epigenetic regulators, a move towards a systems biology approach is nee ...
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 28

 TERMINÉ 

Systems Biology of Stem Cells and Reprogramming (SyBoSS)

Date du début: 1 juin 2010, Date de fin: 30 nov. 2015,

Stem cells are central to emerging concepts in health, medicine and therapy. The realization that specific cell reservoirs retain multipotency for tissue establishment and replenishment has implications for both the emerging field of regenerative therapy and the long standing problems of cancer, ageing and degenerative diseases. Recently the prospects for regenerative therapy have been boosted by ...
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 11

 TERMINÉ 

SUrrogate markers for vascular Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2015,

Diabetes mellitus is a lifelong, incapacitating disease affecting multiple organs. Worldwide prevalence figures estimate that there will be 246 million diabetic patients in 2007 and 380 million in 2025. Presently, diabetes can neither be prevented nor cured and the disease is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular disease) as we ...
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 27

 TERMINÉ 

Beta Cell Therapy in Diabetes (BETACELLTHERAPY)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,

Type 1 diabetes is a serious chronic disease with major health risks and heavy burden on patients and society. It is caused by massive immune-mediated loss of insulin-producing beta cells in the pancreas that can so far not be locally corrected. A cellular allotransplant in the liver can install a new beta cell mass but the size is insufficient and the procedure faces limitations of donor shortage ...
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 18

 TERMINÉ 

Photonic Advanced Research And Development for Integrated Generic Manufacturing (PARADIGM)

Date du début: 1 oct. 2010, Date de fin: 31 mai 2015,

The objective of PARADIGM is to effect a fundamental change in the way photonic integrated circuits (PICs) based on indium phosphide (InP) are designed and manufactured in Europe, with the aim of reducing the costs of design, development and manufacture by more than an order of magnitude and making more complex and capable designs possible than ever before.The key step is to develop a generic plat ...
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 19

 TERMINÉ 

Infectious triggers of chronic autoimmunity (INTRICATE)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2015,

This proposal builds on existing expertise and collaborations of a multidisciplinary Consortium of basic scientists and clinical investigators each of whom has made a substantial individual contribution to understanding the links between infection and autoimmunity. The aim of the INTRICATE Consortium is to prosecute a programme of Translational Research that deliniates the role of infection in the ...
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 13

 TERMINÉ 

Novel immunotherapies for type 1 diabetes (NAIMIT)

Date du début: 1 nov. 2009, Date de fin: 30 avr. 2015,

This proposal will pioneer the concept of tailored interventions with minimal immune system interference in new onset T1DM, leading to beta-cell protection and restoration, based on a solid understanding of the disease pathogenesis. This will enable experimental findings to be adopted for future clinical application. Four work packages are grouped around ‘Reversal of autoimmunity’, in which two ke ...
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 15

 TERMINÉ 

European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2015,

The aim of EU-GEI is to identify the interactive genetic, clinical and environmental determinants involved in the development, severity and outcome of schizophrenia (EU-GEI, Schiz. Res. 2008; 102: 21-6). In order to identify these interactive determinants, EU-GEI will employ family-based, multidisciplinary research paradigms, which allow for the efficient assessment of gene-environment interaction ...
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 27

 TERMINÉ 

The Integrated Neurobiology of Food Intake, Addiction and Stress (NEUROFAST)

Date du début: 1 avr. 2010, Date de fin: 31 mars 2015,

NeuroFAST is a multidisciplinary project, involving ten teams from seven countries, to explore the neurobiology of addiction and eating behaviour and the complex socio-psychological forces that can lead to its dysregulation. These forces include dietary components (including highly palatable foods and alcohol), some of which may have addictive properties, but also cultural and social pressures, ev ...
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 13

 TERMINÉ 

European large-scale functional genomics in the rat for translational research (EURATRANS)

Date du début: 1 avr. 2010, Date de fin: 31 mars 2015,

Genetic studies in model organisms and humans, including human genome-wide association studies, have pinpointed genomic regions that contribute susceptibility to common disease. However, to date, these data have provided limited insights into the genes, molecular pathways and mechanisms underlying disease pathophysiology.The EU FP6 Euratools consortium has been a remarkable success that establishe ...
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 19

 TERMINÉ 

European Consortium for Communicating Stem Cell Research (EuroStemCell)

Date du début: 1 mars 2010, Date de fin: 28 févr. 2015,

The European Consortium for Communicating Stem Cell Research, EUROSTEMCELL, brings together the major current FP6 and FP7 stem cell projects, the European Clinical Research Infrastructure Network, and four internationally recognized European stem cell centres to develop a comprehensive, coordinated platform for collation, dissemination and archiving of information on stem cell biology and regenera ...
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 11

 TERMINÉ 

Gaia Research for European Astronomy Training - ITN (GREAT)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,

Gaia is the ESA cornerstone mission set to revolutionise our understanding of the Milky Way. This proposal will shape a critical mass of new expertise with the fundamental skills required to power the scientific exploitation of Gaia over the coming decade and beyond.The GREAT-ITN research theme is 'Unravelling the Milky Way' focused on four fundamental problems: unravelling the origin and history ...
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 13

 TERMINÉ 

TreatPolyQ – Industrial Academic Initial Training Network towards treatment of Polyglutamine Diseases (TREATPOLYQ)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,

Protein aggregation is a hallmark of many late onset neurodegenerative disorders including Parkinson’s Disease (PD), Alzheimer’s Disease (AD), amyotrophic lateral sclerosis (ALS), prion diseases as well as the group of polyglutamine diseases (polyQ). The aim of this proposal is to create a network of European partners bridging important basic mechanisms involved in proteinopathies, research of mod ...
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 17

 TERMINÉ 

Advanced European Infrastructures for Detectors at Accelerators (AIDA)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

AIDA (http://cern.ch/aida) addresses the upgrade, improvement and integration of key research infrastructures in Europe, developing advanced detector technologies for future particle accelerators, as well as transnational access to facilities that provide these research infrastructures.In line with the European Strategy for Particle Physics, AIDA targets the infrastructures needed for R&D, prototy ...
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 39

 TERMINÉ 

The DNA damage response and breast cancer (DDRESPONSE)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

We will exploit the DNA damage response (DDR) to assess and predict individual susceptibility and response focussed on breast cancer and breast cancer therapies. The 1st targeted therapy based on the DDR is inhibition of PARP by olaparib, which induces synthetic lethality in cancer cells with a specific DDR defect. Our members discovered olaparib, which is currently in Phase II trials. Its use in ...
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 6

 TERMINÉ 

Advanced High-Temperature Reactors for Cogeneration of Heat and Electricity R&D (ARCHER)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

In line with the Sustainable Nuclear Energy Technology Platform (SNETP) Strategic Research Agenda (SRA) and Deployment Strategy (DS), the ARCHER project will extend the state-of-the-art European (V)HTR technology basis with generic technical effort in support of nuclear cogeneration demonstration.The partner consortium consists of representatives of conventional and nuclear industry, utilities, Te ...
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 34

 TERMINÉ 

Ecological Function and Biodiversity Indicators in European Soils (ECOFINDERS)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

The strategic goal of EcoFINDERS is to provide the EC with tools to design and implement soil strategies aimed at ensuring sustainable use of soils, including: i) Characterisation of European soil biodiversity; ii) Determination of relations between soil biodiversity, soil functions and ecosystem services; iii) Design of policy-relevant and cost-effective indicators for monitoring soil biodiversit ...
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 29

 TERMINÉ 

Latin America and Europe Liaison (LAEL)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

"Europe and Latin America have a very similar cultural background and share a common historical heritage. The present proposal aims at strengthening scientific collaborations and research partnerships between research institutions in Europe and in Latin America, in key emerging fields of contemporary science and in particular in • Neuroscience • Biophysics and Molecular Neurobiology • Bionanotechn ...
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 2

 TERMINÉ 

Sculpting the Earth’s topography: insights from modelling deep–surface processes (TOPOMOD)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

TOPOMOD is a training project designed for a team of early-stage and experienced researchers to investigate and model the origin and evolution of topography of the continents over a wide range of spatial and temporal scales and using a multi-disciplinary approach, coupling geophysics, geochemistry, tectonics and structural geology with advanced geodynamic modeling.TOPOMOD involves 8 European resea ...
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 10

 TERMINÉ 

Academic-Industrial Initial Training Network on Innovative Biocompatible Titanium-base Structures for Orthopaedics (BIOTINET)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

BioTiNet ITN is an inter-disciplinary, inter-sectoral and multinational initiative, which has the primary goal of training researchers who will help to improve the overall efficiency of metallic implants in orthopedic treatment by minimizing the stress shielding effect, and promote technical, biological and clinical developments at a pan-European level, for the benefit of all European inhabitants. ...
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 13

 TERMINÉ 

GraphenE-orgaNIc hybrid architectures for organic electronics: a mUltiSite training action (GENIUS)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2014,

"GENIUS aims at offering highest-quality supra-sectoral and cross-disciplinary training to a pool of promising young researchers, in an area at the interface between Supramolecular Chemistry, Materials- and Nano-Science, Physics and Electrical Engineering. GENIUS appointees will be trained in lecture courses, dedicated schools and workshops, and through an ambitious and carefully planned research ...
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 8

 TERMINÉ 

Mathematical Aspects of Quantum Dynamics (MAQD)

Date du début: 1 déc. 2009, Date de fin: 30 nov. 2014,

The main goal of this proposal is to reacha better mathematical understanding ofthe dynamics of quantum mechanicalsystems. In particular I plan to workon the following three projects alongthis direction. A. Effective EvolutionEquations for Macroscopic Systems.The derivation of effective evolutionequations from first principle microscopictheories is a fundamental task of statisticalmechanics. I hav ...
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 3

 TERMINÉ 

Semiconductor nanowires: from fundamental physics to device applications (NANOWIRING)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,

The interest in bottom-up fabricated semiconductor nanowires (NWs) has been growing steadily in the last years due to their potential as basic building blocks of nanoscale devices and circuits. Investigations performed so far try to exploit three unique properties of NWs: First, they are the smallest dimension structures that allow optical guiding and electrical contacting simultaneously. Second, ...
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 12

 TERMINÉ 

Bringing the artificial pancreas home (AP@home)

Date du début: 1 févr. 2010, Date de fin: 31 oct. 2014,

Description In order to improve treatment of diabetes patients at home, the main goal of AP@Home is to build and evaluate an artificial pancreas (AP). The AP will allow automated glucose control: It monitors your blood glucose (sugar) levels and a software algorithm calculates how much insulin to deliver at any time via a built-in insulin in ...
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 15

 TERMINÉ 

Public Engagement with Research and Research Engagement with Society (PERARES)

Date du début: 1 mai 2010, Date de fin: 31 oct. 2014,

PERARES strengthens public engagement in research (PER) by developing multi-annual action plans, involving researchers and Civil Society Organisations (CSOs) in the formulation of research agendas and the research process. It uses debates on science to actively articulate research requests of civil society. These are forwarded to research institutes, and results are used in a next phase of the deb ...
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 28

 TERMINÉ 

High resolution tools to understand the functional role of protein intrinsic disorder (IDPBYNMR)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,

Recent evidence shows that a large share of proteins gain functional advantages by remaining natively unstructured, either completely or partially, thus challenging well-established concepts in structural biology. In order to characterize the highly dynamical nature of such “intrinsically disordered proteins”, and follow their (possible) reorganization by interacting with partners, new integrated ...
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 10

 TERMINÉ 

Metabolic Flux Analysis and Cancer (METAFLUX)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,

"The post-genomic era has been driven by the development of technologies that allow the function of cells and whole organisms to be explored at a molecular level. Metabolomics is concerned with the measurement of global sets of low-molecular-weight metabolites, which represent important indicators of physiological or pathological states of organisms. Such profiles provide a more comprehensive view ...
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 9

 TERMINÉ 

Understanding Transport for Concrete which is Eco friendly iNnovative and Durable (TRANSCEND)

Date du début: 1 oct. 2010, Date de fin: 30 sept. 2014,

Cement is the primary binding phase of concrete. It is millennia old and ubiquitous worldwide. As a building material, it is unrivalled in terms of tonnage used, price per tonne, and CO2 production per tonne. Yet its very success means that cement production account for about 5% of global man-made CO2 emissions.The cement industry urgently requires more sustainable cement based products with equal ...
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 14

 TERMINÉ 

Floer theoretical invariants of low dimensional manifolds (FloerThInLowDim)

Date du début: 1 oct. 2010, Date de fin: 30 sept. 2014,

My main research interests are in low dimensional topology, symplectic geometry and gauge theory. Over the past 20 years, these fields has seen an explosion of activity due to its relevance to string theory.As part of my PhD thesis, I proved an equivalence between two 3-manifold invariants coming from Floer theory. These are Perutz's Lagrangian matching invariants and Ozsvath and Szabo's Heegaard ...
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 2

 TERMINÉ 

DYNAMICS OF INSTITUTIONAL COOPERATION IN THE EUROPEAN UNION (INCOOP)

Date du début: 1 janv. 2010, Date de fin: 31 mai 2014,

This ITN brings together Universities, think-tanks and high-level officials that all share a long-term interest in a better understanding of the functioning of institutions in the European system of Multi-level governance (MLG) and who have extensive academic and practical expertise in this field. Their interdisciplinary knowledge and experience is pooled with the main objective of improving the E ...
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 8

 TERMINÉ 

Word Wide NMR (WW-NMR)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2014,

and institutions specialised in all aspects of NMR spectroscopy in Europe with newly developed laboratories in five other countries. It builds on EU-funded infrastructures and will enable the creation of strategic and sustainable links with nine Partners from countries outside Europe. In return Third Country Partners will gain access to highly sophisticated NMR equipment. NMR spectroscopy is a bro ...
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 7

 TERMINÉ 

Multiscale reinforcement of semi-crystalline thermoplastic sheets and honeycombs (M-RECT)

Date du début: 15 avr. 2010, Date de fin: 14 avr. 2014,

The M-RECT project aims to create multiscale-reinforced semi-crystalline thermoplastics (PEEK and PPS), which will outperform all reinforced polymers in terms of strength, stiffness, creep and mainly damping by upscaling and further developing state of the art production methods, within cost-efficient manufacturing routes. The envisaged multiscale reinforcement will comprise of dispersed straighte ...
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 23

 TERMINÉ 

Collaborative Oncological Gene-environment Study (COGS)

Date du début: 1 mai 2009, Date de fin: 31 janv. 2014,

The overarching goal of COGS is to identify individuals with an increased risk of breast, ovary and prostate cancer. Furthermore, we will evaluate the effect of inherited genetic variation on tumour characteristics and clinical outcome. We will do this through quantifying the role of genetic and environmental/lifestyle risk in the largest data set ever generated. In all, we will include over 200,0 ...
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 16

 TERMINÉ 

Sea Ice Downstream Services for Arctic and Antarctic Users and Stakeholders (SIDARUS)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,

"The overall objective of SIDARUS is to develop and implement a set of sea ice downstream services in the area of climate research, marine safety and environmental monitoring. SIDARUS will extend the present GMES services with new satellite-derived sea ice products, ice forecasting from regional models and validation of sea ice products using non-satellite data. The demand for improved sea ice inf ...
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 8

 TERMINÉ 

Sensitizer Activated Nanostructured Solar Cells (SANS)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,

Widespread uptake of inorganic semiconductor solar cells has been limited, with current solar cell arrays only producing arround 10 GW of the 15 TW (~0.06%) global energy demand, despite the terrestrial solar resource being 120,000 TW. The industry is growing at a cumulative rate of over 40% per annum, even with effects of the financial crisis. However, to contribute to global power this century, ...
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 11