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 TERMINÉ 
Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper ...
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 29

 TERMINÉ 
The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:1) Develop a series of mutant alleles for every gene in the mouse genome2) Determine the phenotypic consequences of each mutation3) Identify mouse models for the complete d ...
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 11

 TERMINÉ 

Integrated Structural Biology Infrastructure (INSTRUCT)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2011,

Structural biology in the next two decades aims to integrate structural knowledge at different resolution levels into specific cellular contexts, with a temporal component, to underpin biomedical sciences. This challenge requires the seamless integration of techniques providing information in different resolution ranges. INSTRUCT will link the information obtained by the major structural biology ...
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 15