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Involvement of Mitochondrial PyruvAte Carrier in Tumorogenesis (IMPACT)

Date du début: 1 juin 2013, Date de fin: 31 mai 2015,

"The role of metabolism in cancer has attracted massive attention in recent years. Several studies highlighted the relevance of aberrant metabolic activities in a number of malignancies. A key node of eukaryotic metabolism is the transport of pyruvate between cytoplasm and mitochondria. Pyruvate, the end product of glycolysis, plays an essential role in cellular metabolism as after transport into ...
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