2 projets européens trouvés
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TERMINÉ
Biomarkers and underlying mechanisms of vulnerability to depression (VULDE)
Date du début: 1 avr. 2015, Date de fin: 1 déc. 2017,
Depression is the leading chronic condition in Europe and fourth leading cause of mortality woldwide. Depression is twice more common in women compared with men, associated with dysregulation of steroid hormones in the HPA-HPG axis, ovarian dysfunction, obesity, and very recently, prenatal stress, but the mechanisms underlying its development are not well understood, yet. The current project aims ...
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TERMINÉ
Non-coding RNAs in neurogenic and neuropathic pain mechanisms and their application for risk assessment, patient stratification and personalised pain medicine (NCRNAPAIN)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
Neuro-immune alterations in the peripheral and central nervous system play a role in the pathophysiology of chronic pain, and non-coding RNAs (ncRNAs) regulate both immune and neuronal processes. Therefore, ncRNAPain proposes that ncRNAs are critically important master switches for chronic pain.ncRNAPain represents a multidisciplinary consortium of clinical partners, molecular and systems-level n ...
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