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17 projets européens trouvés

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 TERMINÉ 
"Exposure to secondhand tobacco smoke (SHS) has been classified as a "Group 1" carcinogen (known human carcinogen) by the International Agency for Research on Cancer and has been shown to have adverse health effects on adults and children, including heart disease and respiratory disorders. Electronic cigarettes (e-cigarettes), the most common “electronic nicotine delivery system”, have irrupted i ...
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 11

 TERMINÉ 
Colorectal cancer (CRC) is increasingly being recognized as a heterogeneous disease with distinct molecular subtypes. These subtypes have different biological processes at the basis of their disease and consequently their prognosis and responses to therapy are also different.We have previously developed molecular diagnostic assays using a single platform on routine FFPE tumour biopsies. These assa ...
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 12

 TERMINÉ 
Smoking and other forms of tobacco consumption are considered the single most important cause of preventable morbidity and premature mortality worldwide. Efforts to reduce the devastation of tobacco-related deaths and illness in the EU consist of the Tobacco Products Directive (TPD), and the ongoing implementation of the WHO Framework Convention on Tobacco Control (FCTC). The main objective of EUR ...
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 13

 TERMINÉ 
Important progress has been made in the field of HPV-disease prevention with the development and implementation of HPV vaccines and HPV DNA screening. In the CoheaHr project, the (cost-) effectiveness of different European preventive strategies will be compared. The goal is to build a reliable and comparable evidence base on the (cost-) effectiveness of these policies implemented under country-spe ...
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 13

 TERMINÉ 
Many anti-angiogenic drugs are clinically used in several types of cancer to block angiogenesis, impair tumor growth, progression and dissemination. Nevertheless, clinical trials report emergence of resistance to treatment and a failure in long-lasting effects of these therapies. To date, resistant patients do not currently have any established, proven alternative therapeutic possibility and the m ...
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 1

 TERMINÉ 

Identification of new colorectal cancer susceptibility genes (Finding CRC genes)

Date du début: 17 juin 2013, Date de fin: 6 juil. 2017,

The overall aim of this proposed project is to discovery new colorectal cancer (CRC) susceptibility genes to better understand the colorectal carcinogenesis process and improve the molecular diagnosis the affected families.CRC is one of the most important causes of morbidity and mortality in occidental countries. An early diagnosis of CRC as well as clinical surveillance of those with an increased ...
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 1

 TERMINÉ 
"Angiogenesis inhibition has proven to be a successful anti-cancer therapeutic approach and anti-angiogenic therapies are currently approved as standard therapy in several types of cancer for their clinically validated beneficial extension of overall survival, progression-free survival and/or time-to-progression in these cancer patients. Nevertheless, in preclinical mouse models of cancer, althoug ...
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 1

 TERMINÉ 
Metastatic cancer remains an incurable disease in the majority of cases and thus development of novel treatment strategies is required. Adoptive T cell therapy is a promising therapy for patients with a wide range of cancers. This therapy involves ex vivo activation and expansion of T cells followed by infusion into patients. Peripheral blood CD4+ and CD8+ T cells can be redirected against tumor-a ...
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 2

 TERMINÉ 
Human papillomavirus (HPV) is responsible for approximately 25% of head and neck cancer (HNC) worldwide and appears to be associated with a better response to treatment and improved prognosis. Evidence suggests that HPV-induced HNC has steadily increased in the USA and some European countries in the last decades. However, whether this is a worldwide phenomenon and specific risk factors are associa ...
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 11

 TERMINÉ 

European Stroke Research Network (EUSTROKE)

Date du début: 1 mars 2008, Date de fin: 31 août 2013,

The European Stroke Research Network (EUSTROKE) will be a collaborative effort that brings together researchers, government, industry, the non-profit sector and patient group associations. This network will put Europe at the forefront of stroke research through its multi-disciplinary research program, high-quality training for European scientists and clinicians, and national and global partnership ...
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 17

 TERMINÉ 
"The goals of the PREHDICT study are to determine prerequisites and strategies for vaccination in European countries and to predict the impact of vaccination on screening programmes. To achieve these goals, a multiple HPV type transmission model will be built to describe the type-specific incidence and clearance of HPV infections. This model will be linked to an individual-based simulation model u ...
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 14

 TERMINÉ 

Development of High Performance Diagnostic Array Replication Technology (HiPerDART)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,

Development of High Performance Diagnostic Array Replication Technology (HiPerDART) As with any new technology, the use of DNA microarrays has presented a number of important obstacles, many of which have limited their ability to move beyond research applications. For example, the data obtained from a traditional microarray experiment can fluctuate dramatically due to small perturbations in assay ...
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 7

 TERMINÉ 

Metagenomics of the Human Intestinal Tract (MetaHIT)

Date du début: 1 janv. 2008, Date de fin: 30 juin 2012,

A detailed understanding of human biology will require not only knowledge of the human genome but also of the human metagenome, defined here as the ensemble of the genomes of human-associated microorganisms. Our proposal focuses on the microorganisms of the gut, which are particularly abundant and complex and have an important role for human health and well-being. We shall implement and integrate ...
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 16

 TERMINÉ 

Pricing Policies and Control of Tobacco in Europe (PPACTE)

Date du début: 1 févr. 2009, Date de fin: 30 avr. 2012,

"Price is the single most important intervention in tobacco control (TC). To protect the health of its citizens the EU now has a major role in regulating tobacco fiscal policy (FP) through a number of EU directives. The aims of these directives initially were to ensure the proper functioning of the internal market. The directives aided harmonization in EU Member States (MS) but now with EU enlarge ...
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 8

 TERMINÉ 
The iNTER Support Action (iSA) Project aims to create a pilot cooperative medical support network constituted by the Hospital Son Espases (former Son Dureta) (Spain), the Instituto Valenciano de Oncología (Spain), the Hospital Vall d’Hebron (Spain), the Hospital Sant Joan de Déu (Spain), the Hospital Regional de Bata (Equatorial Guinea), the Desarrollo 2000 en África NGO (Equatorial Guinea), the H ...
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 11

 TERMINÉ 
Histone H1 participates in both the establishment and stabilization of high-order of chromatin organization through its binding to the internucleosomal DNA. H1 seems to play an important role in regulation of chromatin functions, and particularly in the regulation of gene expression and chromosome condensation.However, our understanding of H1 function is based mainly on in vitro studies and we do ...
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 1

 TERMINÉ 
This project will develop a new approach to vocational training using mobile devices to extend learning activity into daily practice so that theory is fully integrated with practical skills development. It will be developed in the context of oncology nursing. Using smart phones, nurses will be able to communicate with each other and their tutors in real time in the work place and access relevant c ...
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 7