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 TERMINÉ 

A Systems medicine approach to chronic inflammatory disease (SYSCID)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2022,

"The SYSCID consortium aims to develop a systems medicine approach for disease prediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, Twins ...
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 16

 TERMINÉ 
Tissue responses to microbial and endogenous danger signals involve the activation of both resident and monocyte-derived macrophages, as well as the coordinated inducible expression of hundreds of inflammatory genes. Gene transcription is controlled by the information contained in thousands of genomic regulatory elements (enhancers and promoters), which is first read by transcription factors (TFs ...
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 2

 TERMINÉ 
Multispectral Optoacoustic Tomography (MSOT) brings a revolution to bio-optical imaging. Being insensitive to photon scattering, MSOT dramatically improves upon conventional bio-optic barriers by enabling (1) three-dimensional high-resolution optical imaging deep inside tissues (several millimetres to centimetres), by (2) high-scalability, ranging from optical-resolution microscopy to acoustic-res ...
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 6

 TERMINÉ 

PTX3 in Humoral Innate Immunity (PHII)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

The innate immune system includes a cellular and a humoral arm. Structural diversity is a characteristic of humoral fluid phase pattern recognition molecules. These include complement components, collectins, ficolins, and pentraxins. We have used the long pentraxin PTX3, identified by the applicant (cDNA and genomic, mouse and human), as a prototypic fluid phase pattern recognition molecule to ...
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 1

 TERMINÉ 

Generation and maintenance of long-lived memory T cells in humans (PERSYST)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Defining the molecular mechanisms governing memory T cell differentiation and homeostasis is of pivotal importance to generate durable and protective T cell responses against infections and cancers. Considerable knowledge in this regard has been acquired in mouse models but is still limited about human T cells. In particular, some mechanisms are assumed to occur in humans but were never formally d ...
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 1

 TERMINÉ 
ESA-ITN will break through the state of the art in sepsis diagnostics and will train 15 early-stage researchers (ESRs) to determine the clinical potency of a variety of new complementary sepsis biomarkers. These cover the full range of the antiinflammatory response in sepsis, at genetic, molecular and cellular level. Rapid and practical biomarker diagnostics for sepsis will be developed by buildin ...
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 7

 TERMINÉ 
Amyotrophic Lateral Sclerosis (ALS) is a fatal degenerative disorder of the brain and spinal cord affecting some 40,000 individuals in Europe, causing 11,000 deaths each year. Our pioneering work on riluzole showed that it is possible to modify ALS progression but all subsequent trials of potential neuroprotective agents have failed. Thus, drug development in ALS, including trial design, patient s ...
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 12

 TERMINÉ 
A key feature of the immune response is its specificity and macrophages must be able to discriminate precisely between an infectious stimulus and a non-infectious one and tune their response in accordance with the molecular context in which the target particle is recognized. In recent years, scientists have proposed the concept of the phagocytic synapse, to stress the fact that a particle does not ...
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 2

 TERMINÉ 

Epigenetics and microRNAs in Myocardial Function and Disease (CARDIOEPIGEN)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2018,

Heart failure (HF) is the ultimate outcome of many cardiovascular diseases. Re-expression of fetal genes in the adult heart contributes to development of HF. Two mechanisms involved in the control of gene expression are epigenetics and microRNAs (miRs). We propose a project on epigenetic and miR-mediated mechanisms leading to HF.Epigenetics refers to heritable modification of DNA and histones that ...
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 1

 TERMINÉ 
...er Europe. The project will be carried out by the forerunners of robotic surgery in the field of urology. The European Association of Urology (NL), ORSI (BE), the University of Saarland (DE) and the Humanitas Research Hospital (IT) combined their state of the art knowledge and expertise, to develop these training programmes. The partners have a solid track-record on (1) the latest developments in ...
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 4

 TERMINÉ 
Innovative nanoparticle formulation for a miR-133 based treatment of cardiac hypertrophyCardiovascular diseases (CDs) are growing problems worldwide, affecting as much as 1% of the population. The causes include ischemic, toxic, genetic, post-inflammatory and structural defects; often multiple etiologies are present within an individual patient germane to the contraction failing, resulting in a mo ...
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 1

 TERMINÉ 

Getting the Ability of working with disabilities more and more 2016

Date du début: 1 mai 2016, Date de fin: 30 avr. 2018,

This project is applied for by the CO Rock Solid Foundation for international youthwork for HO Humanitas. it will be an EVS placement for 4 volunteers from 4 different countries for a periode of 1 year. Since 2013, Humanitas has hosted these kind of foreign volunteers. this time it will be volunteers from Germany, Italy, Greece and austriaHumanitas is an organisation working in the field of me ...
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 6

 TERMINÉ 

MEsenchymal stem cells to Reduce Liver INflammation (MERLIN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

"Prevalence of liver disease is c6% (29 million people) in the EU with mortality rates from chronic liver diseases estimated at 14.3 per 100.000 in the EU-25 in 2004. Most liver diseases have a significant inflammatory component that underpins liver damage and fibrogenesis, yet current therapies have limited effectiveness. Safe novel anti-inflammatory therapies would satisfy a large unmet need for ...
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 9

 TERMINÉ 

Educate, innovate, advocate: peers pave the way!

Date du début: 1 août 2016, Date de fin: 31 déc. 2017,

“Educate, innovate, advocate: peers pave the way!” is a project designed by 4motion, in close partnership with the European Peer Training Organisation (EPTO), to sustain grassroots youth-led peer education projects and advocate for peer education's unique impact on youth blossoming. The project also includes the sending of 1 European volunteer by 4motion who will contribute to its implementation a ...
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 16

 TERMINÉ 

Advanced Immunization Technologies (ADITEC)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

 TERMINÉ 
This project is focused on the development of novel nanomedicines effective in targeting the immunosuppressive, pro-tumoural, Tumour-Associated Macrophages (TAM) with the aim to manipulate the host’s immune system and improve anti-tumour responses. In most patients, chronic inflammation and immune suppression are the dominant effects in the tumour microenvironment. The infiltration of TAM in tumou ...
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 1

 TERMINÉ 

See the Heart

Date du début: 18 mai 2016, Date de fin: 17 mai 2017,

"Every day, all over the world, ordinary people must flee their homes for fear of death or persecution. Many leave without notice, taking only what they can carry. Many will never return. They cross oceans and minefields, they risk their lives and their futures. When they cross international borders they are called refugees."- United Nations "The Refugee Project"(www.therefugeeproject.org). With " ...
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 5

 TERMINÉ 

"Rights and freedom; Responsibility and duty"

Date du début: 1 mai 2016, Date de fin: 30 avr. 2017,

Human rights and social dialogue are part of our day-to-day life. But a lot of young people in Europe take them for granted. Human rights are fundamental for our lives. Yet, we are reminded way too often that the reality is not perfect. Take the recent news from the Mediterranean Sea and the boats full of migrants. They are risking their lives to start a new life in a democratic country, where hum ...
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 6

 TERMINÉ 

BE CRE8TIVE

Date du début: 1 mai 2016, Date de fin: 30 avr. 2017,

The youth exchange "BE CRE8TIVE" will bring together 40 young people from 5 different European countries to compare their perspectives on the topic of unemployment and employability. We believe that youth unemployment is a serious problem that has serious consequences at the social, economic, political as well as individual level. Although youth unemployment is generally around twice higher than t ...
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 5

 TERMINÉ 

BeTheCuRE (BTCURE)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,

BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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 41

 TERMINÉ 

Getting the Ability of working with disabilities more and more

Date du début: 1 mai 2015, Date de fin: 1 févr. 2017,

This project is applied for by the CO Rock Solid Foundation for international youthwork for HO Humanitas. it will be an EVS placement for 4 volunteers from 4 different countries for a periode of 1 year. Since 2013, Humanitas has hosted these kind of foreign volunteers. (the girl from moldova also has a Romanian passport, so she will be sended by the Romanian partner) Humanitas is an organisation ...
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 6

 TERMINÉ 

Street Workout Innovation

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2016,

“Street Workout Innovation" is a follow-up of the successfully implemented youth exchange of AFSSC in 2015, called « SStay Healthy & LIve Healthy » that combined the elements of sport, healthy diets and first aid training. The young people, who took part in this project came to a conclusion that a deeper education as well as the promotion of healthier lifestyles among young people as well as the h ...
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 5

 TERMINÉ 

Your Choice, Your Future

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2016,

The idea of the youth exchange is to bring together young people from our NGO participating in the exchanges abroad in various European countries and they will be asked to reflect on the drugs issue in Europe. We are facing a renewed increase of drugs consumption in many European countries. Young people often turn to drugs because of social, economic, educational, family or personal problems. Ther ...
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 5

 TERMINÉ 

Let's Dance!

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2016,

"Let´s dance!" is a ground-breaking international youth exchange, which would take place in Luxembourg and which would work on intercultural learning of young people through dancing. This project will bring together 40 young people from Luxembourg, Czech Republic, Macedonia, Poland, Estonia and Italy – all united by one wish to live through a great intercultural experience, using the tool of dance ...
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 7

 TERMINÉ 

Keep Calm and No Drugs

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2016,

This youth exchange project theme is about the use of drugs among young people in the world and in Europe. The spread of drug use is one of the most disturbing phenomena of our time. Drug victims are primarily young people who, through weakness of character, insecure, spirit of transgression or simply for image group, agree to try some drug at first, and then cross the boundaries. A teenager o ...
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 5

 TERMINÉ 

A Sound Mind in a Sound Body

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2016,

Through the working experience of our organization and the partners we have met people coming from different backgrounds and professions. At one the projects organized by our partners, we have met a medical students who proposed a project idea related to health. The idea to do a youth exchange on this topic was really interesting and with the help of the group of 4th year medical students the outs ...
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 5

 TERMINÉ 

Digital Europe

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2016,

The international training course "Digital Europe" is planned to take place in Bitola, Macedonia. This project will bring together 17 youth leaders and youth workers from Macedonia, Romania, Poland, Slovakia, Czech Republic and Italy providing them with an opportunity to gain the necessary skills in higher computerization and also enhance their intercultural experience through using the Internet t ...
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 6

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2015, Date de fin: 30 sept. 2016,

The Erasmus+ project, which is being realised by Humanitas University, is contributing to increasing the attractiveness of the University’s educational offer and increasing interest in higher studies. It expands the students’ awareness that in real terms the obtained diploma contributes to raising of skills, competency, and prepares to the necessity of finding oneself in the labour market not only ...
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 1

 TERMINÉ 

mRNA translational regulation in heart failure (MRNA IN HEART)

Date du début: 1 avr. 2014, Date de fin: 29 août 2016,

Protein synthesis is among the principal biological processes underlying cardiac hypertrophy, an early event in many forms of heart failure (HF). It is associated with worsening of cardiac function after long-term exposure to noxae. The rate-limiting step of protein synthesis is mRNA translation, which is controlled by factors involved in initiation and/or elongation. 4E-BPs regulate the translati ...
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 1

 TERMINÉ 

STI's Education

Date du début: 1 août 2015, Date de fin: 31 juil. 2016,

"STI's Education" training course is the result and a follow-up of the previously developed youth exchange by our association about sexual health of young people. Sexually transmitted infections (STIs) constitute a pandemic and affect all populations, but it is the young people, who are the main victims. 50% of new HIV infections in the world, for example, occur among young people between 15 and 2 ...
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 6

 TERMINÉ 

The Choice is Yours

Date du début: 1 août 2015, Date de fin: 31 juil. 2016,

"It's your choice!" is a youth exchange that aims to educate and raise awareness of young people about drug abuse and related social problems. Drug abuse is a recurring and constant problem. It is influenced a lot by the general attitude of the society against drugs. Deeper insights about this problems will be presented and discussed by Estonian National Institute for Health Development speakers ( ...
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 5

 TERMINÉ 

European urban culture

Date du début: 1 août 2015, Date de fin: 31 juil. 2016,

This youth exchange will bring together 40 participants from 5 different countries (France, Estonia, Italy, Macedonia and Czech Republic). Their skills and competences needed to promote European citizenship among young people. This youth exchanges is about European citizenship. We gained a lot of know-how and experience and developed concrete methodology and tools, which can be used by other NGOs. ...
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 5

 TERMINÉ 

CRE8 Jobs!

Date du début: 1 août 2015, Date de fin: 31 juil. 2016,

The project "Cre8 Jobs" is dedicated to the topic of entrepreneurship, where youth workers and youth leaders get opportunity to learn more about this concept, and also to find ways to create innovative business ideas and make them come true. This training is a follow-up of our first youth exchange realised in October 2014 and that became a success. As the continuation of the topic, we would like t ...
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 6

 TERMINÉ 
"Here we seek to identify the genetic program at the basis of T memory stem cell persistence in vivo and use their properties to improve the adoptive T cell transfer for the treatment of human cancer. Adoptive cell transfer with tumour-specific T lymphocytes is currently under test in the clinic for the treatment of solid tumours such as melanoma. However, the poor persistence in vivo of adoptivel ...
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 1

 TERMINÉ 

LETS CRE8!

Date du début: 1 mai 2015, Date de fin: 1 mai 2016,

"LETS CRE8" youth exchange will bring together 40 young people from Luxembourg, Czech Republic, Estonia, Slovakia and Macedonia. The youth exchange will take place in Luxembourg. Together they will develop strategies to reduce and reuse items that we dont really use anymore in everyday life. In fact, many people have the attic, the basement, the garage etc filled of things stored on each other fo ...
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 5

 TERMINÉ 

Graffiti Culture

Date du début: 1 mai 2015, Date de fin: 1 mai 2016,

"Graffiti Culture" was an ambitious youth exchange that brought together 42 young people from 3 European and 3 South Eastern Europeam countries in order to express themselves through urban art. Urban art is a modern form of expression of young urban citizens. Many of them come from disadvantaged backgrounds and traditional forms of youth participation are not suitable for them. Urban art can be a ...
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 6

 TERMINÉ 

All about RIGHTS

Date du début: 1 mai 2015, Date de fin: 30 avr. 2016,

Human rights are fundamental for our lives but are very often overseen or taken for granted, at least in European countries. Yet, there are still many issues that need to be addressed. We believe that human rights education is very important and it is the civil society that plays significant role in it. Youth organizations have a great chance for an interesting topic for empowering projects but ve ...
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 5

 TERMINÉ 

Protect Yourself, Act Yourself

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2015,

"Protect Yourself, Act Yourself" was the first youth exchange, realised by NGO Connexions asbl and it was aimed for young people coming from 5 European countries: Luxembourg, Poland, France, Bulgaria and Czech Republic. It took place from 22-31 May 2015 and involved 40 young people. The topic of this youth exchange was promotion of healthy sexual behaviors among young people. Since sexually transm ...
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 5

 TERMINÉ 

A Vision of Learning - Gamification!

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2015,

The project "A Vision of Learning - Gamification!" is a true modern initiative of our organization. Our dedication to technology and educating youth about new technological innovations has resulted with a project idea dedicated on Gamification. For the youth exchange in Metz, France, 42 representatives from 6 countries: France, Poland, Czech Republic, Croatia, Turkey and Belgium will gather in or ...
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 6

 TERMINÉ 

TargetIng novel MEchanisms of Resolution in inflammation (TIMER)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

Resolution of inflammation is a key determinant of pathology, and an active process which involves diverse pathways and molecules. The general objective of the TIMER Consortium is to identify and validate new molecules involved in the resolution of inflammation as a basis for the development of innovative therapeutic strategies in chronic inflammatory and autoimmune diseases. The project will invo ...
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 13