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 TERMINÉ 

Synthetic Cellular Signaling Circuits (SynSignal)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

Cellular signaling systems are crucially important for a broad range of critical health and disease areas and high value industrial applications. Signaling systems are the target for more than half of the medicines marketed by the pharmaceutical industry, and form the main R&D area for the nutrition, flavour and fragrance industries. SynSignal is a multidisciplinary high-tech consortium working in ...
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 10

 TERMINÉ 

Signal transduction of Olfactory Receptors to their G protein (SIGT-OR-G)

Date du début: 1 avr. 2013, Date de fin: 30 sept. 2014,

G protein coupled receptors form the largest and most important class of cell surface receptors with a seven transmembrane fold. These proteins mediate diverse cell responses as reaction to input signals like hormones, peptides, light and endogenous ligands. Due to their central role, most drugs on the market target these receptors.In 2011 and 2012 incredible advance has been published in terms of ...
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 1

 TERMINÉ 

Structural Biology of Membrane Proteins (SBMPs)

Date du début: 1 sept. 2008, Date de fin: 31 août 2012,

Membrane proteins (MPs) are known to be key molecules in cellular communications, from signal transduction to transport of ions, metabolites and other molecules. They also participate in the synthesis of ATP, the import of soluble or MPs from the cytosol, and they protect living organisms from toxic factors. The proposal consists in a joint training effort involving the major biophysical methods t ...
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