5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Harvesting the power of a new model organism: stem cells, regeneration and ageing in Macrostomum lignano (MacModel)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
The ‘stem-cell theory’ of ageing posits that the functional decline in adult stem cells is one of the factors contributing to ageing. Importantly, the number of stem cells does not diminish with age in many tissues but rather there are intrinsic and extrinsic changes that affect their functionality. Is it possible to reverse these changes? Experiments in the emerging model Macrostomum lignano sugg ...
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1
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TERMINÉ
Role of telomeres and stem cells in ageing (ROOTS)
Date du début: 1 mai 2012, Date de fin: 30 avr. 2017,
"The impact of a globally ageing population cannot be overstated. It is expected that by the year 2025 over a billion individuals will be over 60 years of age. In order to develop strategies aimed to restore and maintain function in ageing individuals, a better understanding of the molecular pathways and biological processes that are involved in ageing and age-related disorders is urgently needed. ...
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1
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TERMINÉ
MARie CuRIe AGEing Network (MARRIAGE)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
"One of achievements of developed societies has been the remarkable extension of human lifespan. In the upcoming decades the number of Europeans with advanced age will increase dramatically. It is evident that age-associated diseases will become much more prevalent. This poses challenges for society but also opportunities for commercial enterprises that develop strategies to combat deleterious con ...
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11
Participants partenaires
TERMINÉ
Future Internet Technologies for MANufacturing (FITMAN)
Date du début: 1 avr. 2013, Date de fin: 30 sept. 2015,
According to the 2010 EC Competitiveness Report, Manufacturing is still the driving force of Europe's economy, contributing over € 6553 billion in GDP and providing more than 30 million jobs. It covers more than 25 different industrial sectors, largely dominated by SMEs, and generates annually over € 1535 billion (42%) worth of value added services.The mission of the FITMAN (Future Internet Techno ...
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41
Participants partenaires
TERMINÉ
Cellular protein damage control: interactomic analyses of MOAG-4 in C. elegans (AGGREGATION)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2015,
"Several age-related neurodegenerative disorders, such as Alzheimer’s, Parkinson’s and Huntington’s diseases, are characterized by the formation of pathogenic proteins aggregates in the brain. Although some regulators have been identified, how aggregates form during aging is poorly understood.Recently, a modifier of aggregation, MOAG-4, was identified as a positive regulator of aggregation in C. e ...
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