3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Non-Radioactive Molecular Imaging-Driven Drug Development in Oncology (OnQview)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,
Cancer is a leading cause of death worldwide. Fortunately an abundance of cancer drugs are becoming available; the challenge now is to select the most promising. Integrated cancer research and biomarker-driven adaptive and hypothesis-testing clinical trials are imperative. Many tumor characteristics can now be visualized simultaneously, but the necessary tracers have hardly been explored clinicall ...
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2
Participants partenaires
TERMINÉ
Human leukemic stem cells: from identification towards targeting and eradication (huLSCtargeting)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,
Human myeloid leukemias are life-threatening disorders. Although with current therapies the bulk of the tumor is readily eradicated, it is particularly the rare population of leukemic stem cells (LSCs) that is relatively quiescent and is very difficult to target. As a consequence, relapse of the disease occurs frequently resulting in poor survival rates. Nevertheless, remarkable differences do exi ...
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1
Participant partenaire
TERMINÉ
A BLUEPRINT of Haematopoietic Epigenomes (BLUEPRINT)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
In response to the call for a high impact initiative on the human epigenome, the BLUEPRINT Consortium has been formed with the aim of generating at least 100 reference epigenomes and studying them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease. BLUEPRINT will focus on distinct types of haematopoietic cells from healthy individuals and o ...
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