3 projets européens trouvés
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TERMINÉ
"Dissecting the human T cell response to pathogens, allergens, and self-antigens" (PREDICT)
Date du début: 1 juil. 2013, Date de fin: 30 juin 2018,
"The overall goal of this project is to test, in the human system, several hypotheses related to the role of T helper (Th) subsets in immunity and immunopathology. Using an experimental approach that takes advantage of high throughput culture methods and combines the ex vivo analysis of memory T cells with the in vitro priming of naïve T cells, we will dissect the Th cell response to pathogens, al ...
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Participant partenaire
TERMINÉ
IMMUNE RESPONSES TO INFLUENZA VACCINE (IRINVAC)
Date du début: 1 août 2013, Date de fin: 31 juil. 2017,
"Influenza virus continues to represent a major global health problem and the recent pandemic caused by a H1N1 strain of influenza A (swine flu) is a good example of its potential global threat to health. Vaccination again influenza confers in most of the cases protection against the disease, mainly due to a robust humoral response. However, yearly vaccinations are required in order to protect aga ...
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1
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TERMINÉ
New approaches to analyze and exploit the human B and T cell response against viruses (IMMUNEXPLORE)
Date du début: 1 sept. 2010, Date de fin: 31 août 2015,
Immunological memory confers long term protection against pathogens and is the basis of successful vaccination.Following antigenic stimulation long lived plasma cells and memory B cells are maintained for a lifetime,conferring immediate protection and enhanced responsiveness to the eliciting antigen. However, in the case ofvariable pathogens such as influenza virus, B cell memory is only partially ...
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