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10 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 
FOIE GRAS provides innovative training for 13 early stage researchers (ESRs) to answer two critical and unanswered questions: a) Is hepatic bioenergetic remodelling involved in NAFLD pathogenesis, and target for stratification or therapeutic/lifestyle interventions? and b) Is the disruption of the gut-liver axis involved in NAFLD progression? In Western Societies, there has been a recent surge of ...
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 11

 TERMINÉ 

Molecular Mechanisms of Fungal Pathogen Host Interactions (ImResFun)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

ImResFun shall provide state-of-the-art training in infectious disease research and medical immunology targeting the most common human fungal pathogens, the opportunistic Candida species. The key objectives of ImResFun are: (i) to understand how immune cells and infected organs respond to invasion by Candida spp, (ii) to decipher host-defense mechanisms mediating pathogen elimination, and (iii) to ...
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 12

 TERMINÉ 

Supply-rate depression as endogenous anti-epileptic mechanism (ENDOGENOUS AED)

Date du début: 1 sept. 2012, Date de fin: 24 août 2017,

Epilepsy is a prevalent neurological disorder affecting more than 1 % of all people, with the estimated number of 900,000 children and adolescents suffering from active epilepsy in Europe. Most current drugs targeting this disease have important adverse side-effects. An ideal drug would, however, potentiate the endogenous anti-seizure mechanisms that keep most humans epilepsy-free.To date, these n ...
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 2

 TERMINÉ 
"The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the ...
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 22

 TERMINÉ 
Cell adhesion molecules (CAMs) mediate many critical processes in the mammalian brain, including formation and maturation of synapses. CAMs have been implicated in cognitive diseases, such as autism and schizophrenia, as candidate genes. These studies highlight the importance of understanding the mechanisms by which CAMs participate in normal and pathophysiological conditions. Synaptic adhesion-li ...
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 1

 TERMINÉ 

Yeast biodiversity as a source of innovations in food and health (CORNUCOPIA)

Date du début: 1 févr. 2011, Date de fin: 30 avr. 2015,

"Cornucopia will train a new generation of young scientists focusing on less studied yeasts with interesting traits, which could be applied in the food and health sectors. Yeasts are a divergent group of fungi that predominantly exist as unicellular organisms. The baker's yeast Saccharomyces cerevisiae is by far the best known because of its role in producing beverages, baking and recombinant drug ...
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 10

 TERMINÉ 
Genetic studies in model organisms and humans, including human genome-wide association studies, have pinpointed genomic regions that contribute susceptibility to common disease. However, to date, these data have provided limited insights into the genes, molecular pathways and mechanisms underlying disease pathophysiology.The EU FP6 Euratools consortium has been a remarkable success that establishe ...
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 19

 TERMINÉ 
Major objective: It is our aim to develop a lipid based diet that is able to delay or prevent onset of Alzheimer’s disease and related diseases and has a stabilizing effect on cognitive performance in aging. Multiple lines of evidence suggest that there is a large overlap between risk factor of these three diseases. Importantly, there is equally strong evidence that prevention and treatment of the ...
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 19

 TERMINÉ 
The food and health relationship focuses on maintenance of optimal health, both in terms of physiology and new European legislation. Yet, most accepted biomarkers quantify (intermediate) disease endpoints or damage. This has led to major problems in demonstrating health benefits and establishing health claims, and blocks competitive economic and health developments in the food sector. BIOCLAIMS de ...
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 11

 TERMINÉ 
Association between neural representations of stimuli is believed to be an elementary mechanism for learning. However, the ability to prevent inappropriate associations by separating stimuli into coherent subgroups is no less important. Environment exploration triggers immediate-early gene (IEG) expression in environment-specific hippocampal ensembles, suggesting that distinct contexts are represe ...
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