11 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century (EU-ToxRisk)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2021,
The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi ...
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43
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TERMINÉ
Effect of ALlopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome (ALBINO)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of death or long-term disability in infants born at term in the western world, affecting about 1-4 per 1.000 life births and consequently about 5-20.000 infants per year in Europe.Hypothermic treatment became the only established therapy to improve outcome after perinatal hypoxic-ischemic insults. Despite hypothermia and neonatal inte ...
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18
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TERMINÉ
Providing the right care to the right patient with MyeloDysplastic Syndrome at the right time (MDS-RIGHT)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Myelodysplastic syndromes (MDS) are chronic bone marrow malignancies of the elderly, complicated by severe anaemia. MDS significantly affects quality-adjusted survival and it imposes an increasing financial burden on patients and healthcare (HC) systems. The burden of disease is expected to worsen in the future, given the aging EU population and newly identified MDS cases among those diagnosed wit ...
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16
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TERMINÉ
Wireless In-Body Environment (WiBEC)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
WiBEC (Wireless In-Body Environment Communications) is an Innovative Training Network for 16 young researchers, who will be recruited and trained in coordinated manner by Academia, Industry, and Medical Centres. This training will address the Social, Health, and Technology challenges of the H2020:Wireless In-Body Devices. WiBEC’s main objective is to provide high quality and innovative doctoral tr ...
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9
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TERMINÉ
COMPACT BIOPHOTONIC PLATFORM FOR DRUG ALLERGY DIAGNOSIS (COBIOPHAD)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,
Drug hypersensitivity to antibiotics, mainly Beta-lactams (BLCs) affects more than 2.5 million European citizens. Moreover, preventable adverse drug reactions are estimated in additional hospitalization costs of 1750-4500 €/patient. Currently, the allergy diagnosis is mainly based on the information given by invasive, single, and risky in vivo assays. In daily practice, few in vitro diagnostic met ...
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11
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TERMINÉ
Hepatic and Cardiac Toxicity Systems modelling (HECATOS)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
HeCaToS aims at developing integrative in silico tools for predicting human liver and heart toxicity. The objective is to develop an integrated modeling framework, by combining advances in computational chemistry and systems toxicology, for modelling toxic perturbations in liver and heart across multiple scales. This framework will include vertical integrations of representations from drug(metabol ...
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14
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TERMINÉ
Learning from integrated eCare practice and promoting deployment in European regions (Beyond Silos)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,
Description
BeyondSilos enables delivery of integrated care to older Europeans to support them to live independently within the community by providing the ICT tools necessary to join up care pathways across organisations, in particular between social and health service providers. A key area of integration is providing cross-sectoral teams wi ...
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16
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TERMINÉ
Mechanisms of cell dysfunction by aggregation dynamics of polyQ-containing proteins (MechAggrenamics)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
Protein aggregation is a hallmark of several ageing-related neurodegenerative diseases, such as Huntington’s disease (HD), Alzheimer’s disease and prion-mediated diseases. Different cellular pathways influence the rate of aggregation, and clearance of intermediate protein species and aggregates in the cell (for example, autophagy or proteasomal degradation). Many signalling pathways regulate these ...
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1
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TERMINÉ
Realizing the European Network in Biodosimetry (RENEB)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
Creating a sustainable network in biological dosimetry that involves a large number of experienced laboratories throughout the EU will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperated action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently neede ...
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28
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TERMINÉ
EUROPEAN NETWORK for CANCER research in CHILDREN and ADOLESCENTS (ENCCA)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
"ENCCA aims to establish a durable, European Virtual Institute clinical and translational research in childhood and adolescent cancers that will define and implement an integrated research strategy and will facilitate the necessary investigator-driven clinical trials to introduce the new generation of biologically targeted drugs into standard of care for children and adolescents with cancer. This ...
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34
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TERMINÉ
Innovative strategies to generate human hepatocytes for treatment of metabolic Liver diseases: Tools for personalized cell therapy (InnovaLiv)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2014,
Transplantation of donor hepatocytes has become an alternative to liver transplantation for the treatment of liver diseases. However, in addition to the complication imposed by severe shortage of donor livers, adult hepatocytes cannot be expanded in vitro. Autologous transplantation of genetically corrected hepatocytes represents another strategy as it circumvents the need for immunosuppression bu ...
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