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 TERMINÉ 
...will be developed. Different nanoformulation platforms, particularly promising for peptide delivery, controlled release strategies and technologies against proteolytic degradation of peptides will be evaluated in the project. These include lipid-based systems such as lipidic nanocapsules, polymer-based structures such as dendrimers and microgels as well as nanostructured mesoporous silica. The pos ...
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 TERMINÉ 

Analytical Research In ADME profiling (ARIADME) (ARIADME)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

The integration of absorption, distribution, metabolism and excretion (ADME) profiling into early drug discovery has been put forward as a strategy for reducing drug candidate attrition. Europe is challenged to develop novel ADME screening methodologies with increased efficiency and predictive power to profile the multitude of lead compounds currently being generated. The principal objective of th ...
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 6

 TERMINÉ 
Despite the increasing number of macromolecules with potential impact in the treatment of devastating systemic diseases, these therapies have failed to deliver on their expectations because they cannot be administered in the fashion which is most cost efficient and has the highest patient compliance: the oral route. The availability of an oral form of administration could lead to a great improveme ...
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