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Plus de 40 projets européens trouvés

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 TERMINÉ 

BeTheCuRE (BTCURE)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,

BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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 41

 TERMINÉ 

Advanced Research Initiatives for Nutrition & Aquaculture (ARRAINA)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

Sustainable development of European fish farming is dependent on the availability, environmental sustainability of feeds relying less and less on capture fisheries derived fishmeal and fish oil. The European aquaculture industry has made a determined shift towards the use of feeds based on alternative ingredients which continue to ensure the health and welfare of fish and the nutritional value of ...
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 23

 TERMINÉ 
ABSTRESS applies combined, integrated systems biology and comparative genomics approaches to conduct a comprehensive study of the gene networks implicated in the interaction of drought stress and Fusarium infection in legumes. It uses Medicago truncatula as a model to rapidly identify characteristics for introgression into elite pea varieties and a field test of their performance against existing ...
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 15

 TERMINÉ 
"Commercial use of advanced ceramics is limited by the complexity and high costs of implementation; skepticism about the long-term stability and consistency of material properties, coupled with lack of industry-wide standardization, high cost of components and absence of performance tracking deterring the full-scale commercialization of advanced ceramics until recently. However, burgeoning researc ...
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 5

 TERMINÉ 

BRain dEvelopment and Air polluTion ultrafine particles in scHool childrEn (BREATHE)

Date du début: 1 août 2011, Date de fin: 31 juil. 2016,

"Traffic-related air pollution is an important environmental problem that may affect neurodevelopment. Ultrafine particles (UFP) translocate to the brains of experimental animals resulting in local proinflammatory overexpression. As the basic elements for thinking are acquired by developing brains during infancy and childhood, susceptibility may be elevated in early life.We postulate that traffic- ...
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 4

 TERMINÉ 

European Consortium for the Early Treatment of Diabetic Retinopathy (EUROCONDOR)

Date du début: 1 mars 2012, Date de fin: 30 juin 2016,

Diabetic retinopathy (DR), the leading cause of blindness among working-age individuals in developed countries has been classically considered to be a microcirculatory disease of the retina. However, there is growing evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of DR. For this reason, it is reasonable to hypothesize that therapeutic strategies based on n ...
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 18

 TERMINÉ 
StoRRe proposal concerns the area of thermal energy storage by chemical reaction for concentrated solar power plants (CSP). The objective of the project is to develop a new and promising solution for the heat storage with the following characteristics: Mid-term (24h to few days) up to long-term (several months) heat storage High storage density (300-500 kWh∙m3), High temperatures (300-550°C), w ...
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 7

 TERMINÉ 

Rheumatoid Arthritis and Periodontal Inflammatory Disease (RAPID) (RAPID)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2016,

"The most prevalent chronic inflammatory diseases of humans are complex disorders of multifactorial aetiology influenced by genes, the environment and their interactions. Periodontitis (PD) and rheumatoid arthritis (RA) are two such chronic inflammatory diseases associated withsignificant morbidity and mortality, and have recently shown to have a bi-directional association. Moreover, the prevalenc ...
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 15

 TERMINÉ 

Sustainable Organic and Low-input Dairying (SOLID) (SOLID)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2016,

"Organic and low-input dairy farming systems are increasingly noted as delivering multifunctional benefits to the agricultural industry and society but technical and economic constraints prevent widespread adoption. SOLID will deliver an innovative toolbox of novel methodologies that will contribute to the competitiveness of the dairy industry and increase the effectiveness with which these benefi ...
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 26

 TERMINÉ 
The BioStruct-X consortium has 19 partners from 11 EU member and associated states, who lead in facility provision and research in structural biology using high brilliance X-rays, provided by state-of-the art synchrotrons and a free electron laser. BioStruct-X will provide integrated transnational access via 42 installations in four key areas: macromolecular X-ray crystallography, small angle X-ra ...
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 20

 TERMINÉ 

DYNAMIC INTERACTIVE NANOSYSTEMS (DYNANO)

Date du début: 1 nov. 2011, Date de fin: 29 févr. 2016,

"The key and direct objective of DYNANO is to provide training with a deep knowledge and expertise on Dynamic Interactive Nanosystems for biomedical and biotechnological applications on the basis of the existing scientific and technological areas: dynamic chemistry / glycosciences / biology / nanosciences. DYNANO will expose researchers in training to the process of design, generation, optimizatio ...
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 13

 TERMINÉ 
Pancreatic ductal adenocarcinoma (PDAC) causes 34000 deaths in the EU every year. Conventional cancer treatments have close to no impact on this disease. As a result, almost all patients diagnosed with PDAC develop metastases and eventually die. Given this poor outlook, the search for new therapeutics is mandatory. These will have to target relevant cancer pathways and be designed based on the ava ...
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 12

 TERMINÉ 
This proposal aims at setting up an international network of theoretical physicists, developing the methods of quantum integrability and conformal field theory and applying them to the emerging fields of low-dimensional quantum physics. These theoretical studies present, at once, fascinating convergences between exactly solvable statistical models and field theories, such as the topological theori ...
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 5

 TERMINÉ 
Infectious diseases caused by pathogenic micro-organisms are major causes of death, disability, and social and economic disruption for millions of people. During evolution these pathogens have developed intricate strategies to manipulate host defence mechanisms and outwit the immune system. To reduce the burden of infectious diseases it is important to increase understanding of these host-pathogen ...
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 10

 TERMINÉ 

Network for Integrated Cellular Homeostasis (NICHE)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

"There is a need for greater understanding of integrated cellular physiology to exploit cells and to tailor their activities to optimise microbial productivity in synthetic circuits and to limit microbial activity in food and pharmaceutical products. Understanding the integration of the cellular metabolic processes is fundamental to developing and exploiting cells. We have assembled a team of inte ...
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 9

 TERMINÉ 

Integrated non-CO2 Greenhouse gas Observing System (INGOS)

Date du début: 1 oct. 2011, Date de fin: 31 déc. 2015,

InGOS will support and integrate the observing capacity of Europe for non-CO2 greenhouse gases (NCGHG: CH4, N2O, SF6, H2 and halocarbons). The emissions of these gases are very uncertain and it is unknown how future climate change will feedback into the land use coupled emissions of CH4 and N2O. The NCGHG atmospheric abundances will increase further in the future and the emissions of these gases a ...
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 39

 TERMINÉ 

Bioprocess Platform for the A. sojae PGzyme system (PGSYS EXCHANGE)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

PGSYS is an integrated platform for the biosynthesis, tailoring, and final application of the unique pectinase complex from A. sojae, particularly in –but not limited to- the European Food, Beverages, and Environmental industry. PGSYS was born 4 years ago from the pioneering work of Dr. Canan Tari, at Izmir Institute of Technology (Turkey), and further funded by German-Turkish Bodies, and by the E ...
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 3

 TERMINÉ 
Clearing large civilian areas from anti-personnel landmines and cluster munitions is a difficult problem because of the large diversity of hazardous areas and explosive contamination. A single solution does not exist and many mine action actors have asked for a toolbox from which they could choose the tools best fit to a given situation. Some have built their own toolboxes, usually specific to som ...
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 26

 TERMINÉ 

Numerical Relativity and High Energy Physics (NRHEP)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

Numerical relativity, the gauge/gravity duality and trans-Planckian scattering have been tremendously active and successful areas in gravitational/high energy physics in recent years. They are strongly motivated by direct experimental connections: gravitational wave detection, probing strong interactions at the Large Hadron Collider (LHC) and at the Relativistic Heavy Ion Collider (RHIC) and even ...
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 4

 TERMINÉ 

Policy-oriented marine Environmental Research in the Southern EUropean Seas (PERSEUS)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

The overall scientific objectives of PERSEUS are to identify the interacting patterns of natural and human-derived pressures on the Mediterranean and Black Seas, assess their impact on marine ecosystems and, using the objectives and principles of the Marine Strategy Framework Directive as a vehicle, to design an effective and innovative research governance framework based on sound scientific knowl ...
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 55

 TERMINÉ 

Marine Microbial Biodiversity, Bioinformatics and Biotechnology (MICRO B3)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

Micro B3 will develop innovative bioinformatic approaches and a legal framework to make large-scale data on marine viral, bacteria; archaeal and protists genomes and metagenomes accessible for marine ecosystems biology and to define new targets for biotechnological applications. Micro B3 will build upon a highly interdisciplinary consortium of 32 academic and industrial partners comprising world-l ...
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 32

 TERMINÉ 
The ReUseWaste network will i) provide new ideas and systems that lead to a major rethink in the current, established animal waste management systems, ii) train a group of 13 young researchers in developing new technologies for socially and environmentally sustainable utilisation of the valuable organic matter and nutrient ressources in animal waste and iii) provide companies with both improved an ...
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 9

 TERMINÉ 
FERTIPLUS will identify urban and farm organic wastes that can be used to recycle nutrients into agriculture as biochar, compost or combinations of them. Urban and farm organic residues are a large source of nutrients and today not used to its full potential. FERTIPLUS will assess and use this potential and contribute to sustainable crop production and soil productivity and quality across regions ...
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 14

 TERMINÉ 

European Training and Research in Peritoneal Dialysis (EUTRIPD)

Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,

Peritoneal dialysis (PD) and haemodialysis (HD) are life-saving renal replacement therapies for more than 200,000 patients with chronic kidney disease in Europe, and this number increases annually. Although PD and HD have similar mortality rates, PD offers major advantages in terms of quality of life, costs, home-based treatment opportunities and early patient survival. Moreover, PD, rather than H ...
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 13

 TERMINÉ 

Aerial Robotics Cooperative Assembly System (ARCAS)

Date du début: 28 nov. 2011, Date de fin: 27 nov. 2015,

Description The ARCAS project proposes the development and experimental validation of the first cooperative free-flying robot system for assembly and structure construction. The project will pave the way for a large number of applications including the building of platforms for evacuation of people or for landing aircrafts, the inspection an ...
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 12

 TERMINÉ 

FP7 High Luminosity Large Hadron Collider Design Study (HILUMI LHC)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

The Large Hadron Collider (LHC) is the largest scientific instrument ever built. It has been exploring the new energy frontier since 2009, gathering a global user community of 7,000 scientists. It will remain the most powerful accelerator in the world for at least two decades, and its full exploitation is the highest priority in the European Strategy for Particle Physics, adopted by the CERN Counc ...
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 16

 TERMINÉ 

New Technologies and Production Tools for Complex Protein Biologics (ComplexINC)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

ComplexINC conceptualizes and systematically generates advanced tool-kits to enable high-throughput assembly of complex biologics and metabolic pathways in eukaryotic expression systems, for micro- to large scale production of high-quality protein specimens for drug discovery and as bio-therapeutics. Essential parts of these tool-kits will be innovative next-generation HT DNA assembly pipelines fo ...
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 8

 TERMINÉ 
In hematopoiesis, failure to maintain homeostasis and regenerative functions result in a multitude of hematological malignancies, including myelodysplastic syndromes, lymphomas and leukemias, that represent a medical challenge and a large socioeconomic burden because of the large number of affected patients of all age groups. Although hierarchical organization of the hematopoietic system has been ...
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 12

 TERMINÉ 

NOVEL MECHANISMS INACTIVATING CHECKPOINT RESPONSE (CHECKPOINT-INACT)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

Eukaryotic cells need to preserve the integrity of their genomes. Conditions resulting in increased genome instability, defined as the generation and amplification of mutations and chromosomal aberrations, are associated with cancer predisposition and human pathologies. The DNA damage checkpoint acts as a surveillance mechanism that safeguards genome integrity in response to genotoxic insults. Whi ...
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 1

 TERMINÉ 
Our knowledge of the causative links between subsurface processes, resulting unrest signals and imminent eruption is, today, wholly inadequate to deal effectively with crises of volcanic unrest. The VUELCO project consortium has come together for a multi-disciplinary attack on the origin, nature and significance of volcanic unrest from the scientific contributions generated by collaboration of ten ...
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 10

 TERMINÉ 

Evolution and Transfer of Antibiotic Resistance (EVOTAR)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,

Antibiotics are essential therapeutics in the treatment of bacterial infections. However, the indiscriminate use of antibiotics has led to the emergence of antibiotic resistant bacteria that pose a major threat to human health as options for treating infections by these bacteria have become limited. The evolution, emergence and spread ofantibiotic resistance genes are still only poorly understood ...
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 19

 TERMINÉ 
"In order to be able to maximize the benefits from reuse and recycling technologies projects a larger systemic analysis of the environment is needed, an enlargement of the traditional narrow planning and management approaches, and a growing sensitivity to decision-making associated with multi-objective, multi-purpose actions and multi uses parameters. However, the problem is not centered on the la ...
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 13

 TERMINÉ 

Neutron stars as a laboratory for dense matter (NSlabDM)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,

Neutron stars are a unique laboratory for testing matter under extreme conditions. The aim is to understand neutron star observables, such as the mass, typical radii, cooling evolution, magnetic fields or rotation, in terms of a plausible scenario for its interior.Over the last years a particular effort has been invested in studying matter with strange content inside neutron stars. To this end our ...
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 1

 TERMINÉ 
The development of therapeutic vaccines often includes the use of synthetic small molecule antigen constructs to elicit immune response. However, many subunit antigen vaccines are less immunogenic than those employing attenuated microorganisms. As a result, they often require co-administration with an adjuvant or immunostimulating complex, a substance that is itself not necessarily immunogenic but ...
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 1

 TERMINÉ 

HEPATITIS C VIRUS AND HOST LIPOPROTEIN METABOLISM (LIPOHCV)

Date du début: 1 sept. 2011, Date de fin: 31 août 2015,

Over 3% of the world population is chronically infected by the hepatitis C virus (HCV). Chronic infection is associated with liver disease that leads to fibrosis and cirrhosis and ultimately to hepatocellular carcinoma (HCC). There is no vaccine for HCV and the current treatment is only partially effective and toxic. Consequently, HCV infection is one of the leading causes of liver transplantation ...
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 1

 TERMINÉ 

"Flavor, Unification and Symmetries from Strings" (FUSS)

Date du début: 1 mars 2012, Date de fin: 31 août 2015,

"The proposed research program takes place in the context of High Energy Physics and, more precisely, in the subfield known as string phenomenology. The main goal is to develop the potential of string theory to produce realistic models of Particle Physics and Cosmology, as well as to understand the interplay between Quantum Gravity and the phenomenology of such models.The proposed line of research ...
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 1

 TERMINÉ 
"The initial training network CSI: ENVIRONMENT aims at training 16 young scientists in the discipline of compound-specific isotope analysis (CSIA) for environmental and forensic investigations. Linking sources and sinks of organic contaminants is a major challenge in contemporary environmental science. Chemicals can be released to the environment when leaving their field of application, intended o ...
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 11

 TERMINÉ 
Agricultural production requires the use of herbicides as an essential tool to control weed infestations. Associated environmental and economic concerns have led to the creation of European policy that encourages farmers to optimize their use. These components are part of the agronomical basis of site-specific weed management (SSWM), whose efficient development somehow relies on the use of remote ...
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 2

 TERMINÉ 
Mental disorders constitute a human and economic burden for developed countries. Many mental disorders have been linked to serotonin dysfunction, but the precise mechanisms underlying these defects are not well understood. Serotonin Related Mental Disorders (SRMD) are multigenic, which makes the identification of these mechanisms a very difficult task. Understanding the molecular mechanisms that g ...
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 1

 TERMINÉ 

The molecular process and functional consequences of adaptation (ADAPT_EVOL)

Date du début: 1 sept. 2011, Date de fin: 31 août 2015,

"Adaptation is the key concept in Evolutionary Biology. Understanding adaptation has important implications for basic and applied science since adaptation underlies processes such as the ability of species to survive in changing environments, resistance to antibiotics and cancer chemotherapies, and host-pathogen interactions. The recent increase in availability of whole genome sequences makes it p ...
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 1