4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Integrative Analysis of Gene Functions in Cellular and Animal Models of Pancreatic Cancer (CAM-PAC)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Cancers are genetic disease arising from the accumulation of multiple molecular alterations in affected cells. Large-scale genomic, transcriptomic and proteomic analyses have established comprehensive catalogues of molecules which are altered in their structure and/or abundance in malignant tumors as compared to healthy tissues. Far less developed are concepts and methods to integrate data from di ...
Voir le projet
18
Participants partenaires
TERMINÉ
Targeting Src-family tyrosine kinases in chronic autoimmune and inflammatory diseases (TARKINAID)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
The project aims to develop novel inhibitors of chronic autoimmune and inflammatory diseases by targeting members of the Src tyrosine kinase family. Src-family kinases have recently emerged as major therapeutic targets in malignant diseases but their suitability as potential targets of inflammatory diseases has not yet recieved widespread acceptance. On the other hand, members of the applicant con ...
Voir le projet
11
Participants partenaires
TERMINÉ
Targeting the tumour microenvironment to improve pancreatic cancer prognosis (EPC-TM-Net)
Date du début: 1 févr. 2011, Date de fin: 31 juil. 2014,
Pancreatic cancer is one of the most lethal human cancers with a five-year survival rate of less than 5%. Late presentation and a high level of resistance to chemotherapeutic drugs are among the major reasons for this dismal prognosis. The presence of the highest degree of desmoplasia among all solid tumours and the fact that chronic inflammatory pancreatic disease is associated with an increased ...
Voir le projet
17
Participants partenaires
TERMINÉ
Resolve Chronic Inflammation and Achieve Healthy Aging by Understanding Non-regenerative Repair (RESOLVE)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2013,
"RESOLVE has been outlined to better understand the regulatory networks that control the devel-opmental processes in organ repair and to identify mechanisms which cause the termination of regu-lar organ development leading to fibroproliferative wound healing. Fibroproliferative wound healing represents a major pathology in elderly people shifting regular organ development into progressive organ fi ...
Voir le projet