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 TERMINÉ 
The non-innocence of specific ligands in transition metal complexes is well-documented. For example, mesoionic carbenes engage in bond activation processes via reversible hydrogen capture. Such cooperativity between the metal center and the ligand flattens the potential energy surface of a catalytic reaction and hence rises the competence of the catalyst, thus entailing higher turnover numbers as ...
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 2

 TERMINÉ 

Platform foR European Preparedness Against (Re-)emerging Epidemics (PREPARE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Far from receding, the threats posed by infections with epidemic potential grow ever greater. Although Europe has amongst the best healthcare systems in the world, and also the world’s supreme researchers in this field, we lack co-ordination and linkage between networks that is required to respond fast to new threats. This consortium of consortia will streamline our response, using primary and sec ...
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 27

 TERMINÉ 
Water is the first molecule to come into contact with biomaterials in biological systems and thus essential to the processes of biodegradation, biocompatibility and biofouling. Despite this fact, little is currently known about how biomaterials interact with water. This knowledge is crucial for the development and optimisation of novel functional biomaterials for human health (e.g. biosensing devi ...
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 1

 TERMINÉ 
Coronary artery disease (CAD) is the leading cause of death in high-income countries. Invasive coronary angiography (ICA) is the reference standard for the diagnosis of CAD and allows immediate therapy. However, only 40% of patients undergoing ICA actually have obstructive CAD and ICA has relatively rare but considerable risks. Coronary computed tomography (CT) is the most accurate diagnostic test ...
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 38

 TERMINÉ 
Transition to adulthood is the period of onset of most of the serious mental disorders that disable or kill in adult life. Current service configuration of distinct Child and Adolescent Mental Health (CAMHS) and Adult Mental Health (AMHS) Services is considered the weakest link where the care pathway should be most robust. Transition-related discontinuity of care is a major socioeconomic and socie ...
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 14

 TERMINÉ 

Heart OMics in AGEing (HOMAGE)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2019,

As more people survive into old age, the prevalence of heart failure (HF), one of the most common and debilitating diseases in older people, will rise still further. Delaying or preventing HF will have great benefit to those at personal risk, their families, society and the economy. HOMAGE aims to provide a biomarker (BM) approach that will a) help identify i. patients at high risk of developing ...
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 22

 TERMINÉ 
The requirement for sustainable food production is a global issue to which the EU contributes as a major livestock producer. It is critical to improve animal production efficiency while sustaining environmentally friendly milk production. More profitable dairy production requires increased milk yield, cow health, longevity and fertility; reduced environmental footprint and optimised use of inputs. ...
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 17

 TERMINÉ 
"University College Dublin (UCD) proposes a new Postdoctoral training and career development Fellowship Programme, ENERGY21. This programme will maximise the career development of the next generation of researchers in a range of energy-related fields that promise new and exciting opportunities. The programme is characterised by transparency and openness in selecting excellent researchers, grantin ...
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 1

 TERMINÉ 

Ensuring the Integrity of the European food chain (FOODINTEGRITY)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,

Food Integrity “the state of being whole, entire, or undiminished or in perfect condition”.Providing assurance to consumers and other stakeholders about the safety, authenticity and quality of European food (integrity) is of prime importance in adding value to the European Agri-food economy. The integrity of European foods is under constant threat from fraudulently labelled imitations that try to ...
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 64

 TERMINÉ 
This resubmitted Career Integration Grant (CIG) proposal is for a researcher that has been in the USA for 3 1/2 years. The overarching objective of this novel proposal is to create a methodology and implementation environment that fosters collaborative stakeholder interaction for the purposes of optimised Building Life Cycle (BLC) performance analysis, in a physical and virtual environment called ...
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 1

 TERMINÉ 

How does Nitric Oxide (NO) regulate crop pathogen virulence? (NO CROP PATHOGEN)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

"Fungal pathogens cause disease in important cereal and horticultural crop plants dramatically reducing yields and quality. Preventing fungal disease in crop plants would ensure global food security and reduce agricultural inputs with respect to fungicide application. Following the recognition of microbial attack both plants and animals produce a nitric oxide (NO) burst which is directly antimicro ...
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 1

 TERMINÉ 
The motivations that originate this project stem from the worldwide reconfiguration processes that electric power systems are currently undergoing. On one hand, there is the development and installation of generation plants based on renewable energy resources, e.g., wind and solar plants, whose stochastic nature has to be properly considered in the transient analysis of power systems. On the other ...
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 1

 TERMINÉ 

"FLUOR21 : Synthesis, structure and function of fluorinated systems" (FLUOR21)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

"Organofluorine chemistry has played a significant role in the majority of the spectacular scientific and technological developments of thepast century although this is not widely recognised even by the scientific community. Fluoroorganic molecules are key components in anever increasing number of high-value commercially important products particularly in the life science industries. The use of fl ...
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 9

 TERMINÉ 
TRANSMANGO aims to obtain a comprehensive picture of the effects of the global drivers of change (climate, economic concentration and market structure, financial power, resource competition, marginalization, property rules, geo-political shifts, consumer preferences, consumption patterns and nutritional transition) on European and global food demand and on raw material production (and, consequent ...
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 13

 TERMINÉ 

Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
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 19

 TERMINÉ 

Productivity, Non-Tariff Measures and Openness (PRONTO)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

The latter half of the 20th century saw a successful international effort to reduce tariffs. These achievements, however, were undone by the subsequent proliferation of non-tariff measures (NTMs) to limit international trade and investment. These measures take a variety of forms and include safety regulations, environmental standards, and corporate tax incentives, all of which influence both trade ...
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 11

 TERMINÉ 

Molecular basis of the outer membrane permeability (TRANSLOCATION)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

Overcoming the barriers that the cell envelope and efflux pumps provide to Gram-negative bacteria is a major bottleneck in the discovery and development of new antibiotics. To respond to this Call we are extending our current network on antibiotic translocation and propose an ambitious project ranging from identification of novel resistance mechanisms in clinical bacterial isolates to crystallizat ...
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 28

 TERMINÉ 

RETURN – Rethinking Tunnelling in Urban Neighbourhoods (RETURN)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

"This project addresses important challenges at the forefront of geotechnical engineering and building conservation by introducing an entirely new workflow and largely unexploited data source for the predic-tion of building damage from tunnel-induced subsidence. The project will also make fundamental and ground-breaking advances in the collection and processing of city-scale, aerial laser scanning ...
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 1

 TERMINÉ 
Rapidly developing markets such as green construction, energy harvesting and storage, advanced materials for aerospace, electronics, medical implants and environmental remediation are potential key application targets for nanomaterials. There, nanotechnology has the potential to make qualitative improvements or indeed even to enable the technology. Impacts range from increased efficiency of energy ...
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 26

 TERMINÉ 
Nanomedicine and Nanosafety rely on the same fundamental interactions between the nanoparticle interface and the biological milieu surrounding it, and it is this “corona” of proteins and other biomolecules that form at the bio-nanointerface that determines the fate and behaviour of nanomaterials. Understanding, classifying and predicting nanoparticle coronas from their physicochemical properties ...
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 2

 TERMINÉ 
"Ageing is the gradual and irreversible breakdown of living systems associated with the advancement of time, which leads to an increase in vulnerability and eventual mortality. Despite recent advances in ageing research, the intrinsic complexity of the ageing process has prevented a full understanding of this process, therefore, ageing remains a grand challenge in contemporary biology. In AGELESS, ...
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 1

 TERMINÉ 

Operational Potential of Ecosystem Research Applications (OPERAs)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,

Human use and exploitation of the biosphere is increasing at such a pace and scale that the sustainability of major ecosystems is threatened, and may not be able to continue to function in ways that are vital to the existence of humanity. Re-framing environmental resource use has led to the emergence of the concepts of ecosystem services (ES) and natural capital (NC). This discourse indicates not ...
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 27

 TERMINÉ 

Synthetic Cellular Signaling Circuits (SynSignal)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

Cellular signaling systems are crucially important for a broad range of critical health and disease areas and high value industrial applications. Signaling systems are the target for more than half of the medicines marketed by the pharmaceutical industry, and form the main R&D area for the nutrition, flavour and fragrance industries. SynSignal is a multidisciplinary high-tech consortium working in ...
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 10

 TERMINÉ 

Sustainable Innovative Mobilisation of Wood (SIMWOOD)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"SIMWOOD presents a novel idea for an innovative, integrated approach to multifunctional forestry and enhanced wood mobilisation across European forest regions. The project targets a multitude of forest owners and stakeholders to spread integrated, transferable solutions and viable policies to unlock immobile forest resources and ensure sustainable forest functions. A novel pan-European Informatio ...
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 29

 TERMINÉ 
Vitamin D deficiency has significant implications for human health and impacts on healthy growth and development and successful aging. Fundamental knowledge gaps are barriers to implementing a safe and effective public health strategy to prevent vitamin D deficiency and optimize status. ODIN will provide the evidence to prevent vitamin D deficiency in Europe and improve nutrition and public health ...
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 32

 TERMINÉ 

Long-term effects of early nutrition on later health (EARLYNUTRITION)

Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,

Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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 40

 TERMINÉ 
Worldwide figures show that there were 160,000 incidences of melanoma in 2002, whilst 39,000 died from the disease. These upward trends are worrying, as malignant melanoma is one of the most difficult cancers to treat, due to its ability to spread quickly and its resistance to standard chemotherapeutic agents. In order to counteract this trend, targeted therapies that inhibit melanoma metastasis a ...
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 7

 TERMINÉ 
MEDCHANGe focuses on the analysis of the relationships between global networks (Internet), flows (virtual and spatial mobilities of individuals, information i.e. migration also in light of gender issues such those of Moroccon female migrants; climate change migrants; tourism and heritage valorisation flows) and geographical localities in terms of local development and marginalisation/segregation. ...
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 6

 TERMINÉ 
Assuming an annual birth rate of 10.25 births/1,000 population approximately 25,000 Extremely Low Gestational Age Newborns are born every year in the EU. Conservative figures estimate that approximately half of all these babies will develop low blood pressure and require treatment. However, no uniform criteria exist to define hypotension and the evidence to support our current management strategie ...
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 17

 TERMINÉ 
Nanomedicine offers capability to significantly change the course of treatment for life-threatening diseases. Many of the most significant current therapeutic targets, to be viable in practice, require the efficient crossing of at least one biological barrier. However, the efficient and controlled crossing of the undamaged barrier is difficult. The range of small molecules that can successfully do ...
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 9

 TERMINÉ 

Accurate Waveforms for Extreme/Intermediate-mass-ratio-inspirals (AWE) (AWE)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2017,

"The age of gravitational wave astronomy will soon be upon us. Initially the most likely sources to be detected by ground-based detectors will be compact binary systems. This project proposes to deepen our understanding of such two-body systems by computing accurate gravitational waveforms from extreme- and intermediate-mass-ratio systems. The latter is expected to be directly observed in the LIGO ...
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 1

 TERMINÉ 

Toward a Phenomenology of the Anxious Body (TPAB)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2017,

"The project, Toward a Phenomenology of the Anxious Body (TPAB), is a study of anxiety, which employs an interdisciplinary methodology involving philosophy, cognitive science, and psychoanalysis. Anxiety is the most common form of mental illness in the US and UK, affecting 18% of the population in the US and 13% in the UK. Despite this, a rigorous analysis of anxiety at both an experiential and co ...
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 1

 TERMINÉ 

CI-NERGY Smart cities with sustainable energy systems (CI-NERGY)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

The CI-NERGY Marie Curie Initial Training Network (ITN) aims to train young scientists to develop urban decision making and operational optimisation software tools to minimise non-renewable energy use in cities. The training will be carried out by a close collaboration of six of the best academic research centres and four leading industrial companies from the energy and software technology sector ...
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 11

 TERMINÉ 

Sustainable Pavements & Railways Initial Training Network (SUP&R ITN)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"The design, construction, maintenance, use and end-of-life management of road pavements and railways is associated with a number of important impacts on the environment; namely the consequences of energy consumption, unsustainable use of materials/resources, waste generation and release of hazardous substances into the environment. It is estimated that over 80% of all these environmental impacts ...
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 10

 TERMINÉ 
"The YEASTCELL ITN will train 11 Early Stage Researchers for productive careers as research scientists and leaders in the public or private yeast biotechnology sectors. Yeast biotechnology spans fundamental and applied research and is an area with an immediate need for highly trained researchers to advance knowledge and to develop new applications. The training consortium comprises 9 Public Sector ...
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 13

 TERMINÉ 

Time-Domain RF and Analog Signal Processing (TDRFSP)

Date du début: 1 sept. 2012, Date de fin: 31 août 2017,

"One of the most important developments in the communication microelectronics in the last decade was the invention and popularization of “Digital RF”. It transforms the radio frequency (RF) analog functionality of a wireless transceiver into digitally-intensive implementations that operate in time-domain. They are best realized in mainstream nanometer-scale CMOS technologies and easily integrated ...
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 2

 TERMINÉ 

Drug Discovery and Development for Novel Eye Therapeutics (3DNET)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

"Age-related macular degeneration, diabetic retinopathy, and corneal inflammation are significant causes of irreversible blindness with increasing prevalence as the EU population ages and the “diabetes epidemic” expands. There is an unmet clinical need for more effective treatments to halt or reverse these diseases.Many EU pharmaceutical and biotechnology companies, with established processes for ...
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 5

 TERMINÉ 
"The overarching aim of this research project is to study the labour-market returns to postsecondary education in both Europe and the United States. Postsecondary educational offerings are constantly evolving, but the labour-market returns to many of these offerings are not well understood. Dr. Jepsen will use state-of-the-art techniques to produce and disseminate peer-reviewed economics journal ...
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 1

 TERMINÉ 

Targeting cardiac fibrosis for heart failure treatment (FIBRO-TARGETS)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

The Fibro-Targets project is a multi-disciplinary 4 years program involving 10 partners ambitioning “the identification, characterisation and validation of in vitro and in vivo models of novel therapeutically relevant targets” for myocardial interstitial fibrosis (MIF) in heart failure. The project is based on the hypothesis that the intervention on novel fibrosis-related targets involved in the p ...
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 11

 TERMINÉ 

Geo-Spatial Modelling Informing Policy (GeoSInPo)

Date du début: 1 août 2014, Date de fin: 31 juil. 2017,

The aim of this fellowship is for the applicant – Dr. Harutyun Shahumyan – to move from University College Dublin (UCD) in Ireland to University of Maryland (UMD) in US for two years and then return and build on his research at UCD for another year, for the purposes of enhancing his training in integrated modelling supporting smart and sustainable growth; and to provide complementary skills traini ...
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 1