5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
A Gateway to European Kidney Research Resources - KidneyConnect (KidneyConnect)
Date du début: 1 août 2013, Date de fin: 31 juil. 2016,
Diabetes, Cardiovascular and Chronic kidney (DCC) -diseases are relentlessly increasing globally, causing enormous human suffering, premature deaths and unsustainable costs. Leading European research has indisputably pointed that the kidney filtration barrier and its epithelial cell, the podocyte, is a common denominator for the DCC-diseases. However, European excellence and expertise have remaine ...
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19
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TERMINÉ
Infectious triggers of chronic autoimmunity (INTRICATE)
Date du début: 1 nov. 2010, Date de fin: 30 avr. 2015,
This proposal builds on existing expertise and collaborations of a multidisciplinary Consortium of basic scientists and clinical investigators each of whom has made a substantial individual contribution to understanding the links between infection and autoimmunity. The aim of the INTRICATE Consortium is to prosecute a programme of Translational Research that deliniates the role of infection in the ...
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13
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TERMINÉ
The role of the transcription factor GATA3 in kidney function and disease (GATA3 in KIDNEY)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2015,
Mutations in GATA3, a dual zinc-finger transcription factor, cause the autosomal dominant hypoparathyroidism, deafness, renal dysplasia (HDR) syndrome, and down-regulation of GATA3 results in clear cell renal cell carcinoma. The renal abnormalities in HDR patients consist of cysts, renal aplasia/hypoplasia, mesangioproliferative glomerulonephritis, and vesicoureteral reflux. In the developing kid ...
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1
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TERMINÉ
Translational Science for Vascular Inflammation and Remodelling (TranSVIR)
Date du début: 1 déc. 2009, Date de fin: 30 nov. 2013,
The rapid advance of biology is providing new insights into the causes of some of today’s most pressing medical problems as well as huge opportunities to develop and evaluate novel and more effective treatments. The challenge is to exploit these advances effectively and this will require a new breed of translational scientist with expertise in a specific discipline coupled with a broad understandi ...
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6
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TERMINÉ
Evaluation of epigenetic biomarkers in prostate cancer patients before and after hormone ablation therapy (Epigenetic marker)
Date du début: 1 nov. 2009, Date de fin: 31 oct. 2012,
Prostate cancer is among the leading tumor types in men in the Western world. The heterogeneity of prostate cancer provides difficulties in tumor classification and decision-making for therapies. The establishment of new biomarkers is essential to develop individual treatments and facilitate tumor categorization. Therapies include hormone deprivation, which initially leads to tumor regression, but ...
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