Date du début: 1 janv. 2017,
Date de fin: 31 déc. 2021,
Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
Date du début: 1 sept. 2015,
Date de fin: 31 août 2020,
Stroke is the second leading cause of death in the world population. When not fatal, stroke often results in disability, due to motor and cognitive impairments, and secondary health problems affecting not only patients but also their families. Building on emerging preclinical and pilot clinical evidences, RESSTORE will focus on the clinical assessment of regenerative cell therapy to improve stroke ...
Date du début: 1 oct. 2013,
Date de fin: 30 sept. 2017,
The goal of SYMPATH is to advance clinical development of therapeutic vaccines targeting α-synuclein (aSyn)-driven neurodegenerative diseases (ND). It addresses Parkinson’s disease (PD) and multiple system atrophy (MSA), two synucleopathies, for which no causal therapy exists. Ultimately, both lead to patient disability and death, which along with patient number (PD) and age of onset (MSA, PD) def ...
Date du début: 1 mars 2012,
Date de fin: 30 avr. 2017,
The prevalence of diabetes in people ≥ 65 years approaches 25% (40% of all patients with diabetes are > 65 years). This number will increase 4-fold in people > 70 years in 2050. Diabetes results in a high personal and social health burden, and a significant public health burden in terms of rising healthcare costs. Diabetes is associated with increased functional decline in older people and may exp ...
Date du début: 1 nov. 2010,
Date de fin: 31 oct. 2015,
"The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular and organ levels which interact to form the basis for proarrhythmic mechanisms in AF. Numerous individual and environmental ...
Date du début: 1 mai 2012,
Date de fin: 30 avr. 2014,
"Understanding of normal and abnormal cardiac excitation and contraction requires the integration of knowledge of myocyte electrophysiology and mechanics with knowledge of dynamic myocardial architecture.The myocardium is structured as stacked 4-6 cells thick (~100 µm) laminae of myocytes, which have a complex architectural arrangement throughout the cardiac wall and have localised regions of abru ...
Date du début: 1 mai 2008,
Date de fin: 31 oct. 2011,
"Hearing loss is one of the most common chronic health conditions in the elderly population with important implications for patient quality of life. The diminished ability to hear and to communicate is frustrating in and of itself, but the strong association of hearing loss with depression and functional decline adds further to the burden on individuals who are hearing impaired. Hearing loss can ...
Date du début: 1 nov. 2008,
Date de fin: 30 avr. 2011,
Most nutraceutical SMEs have a limited access to the information needed for identifying the impact of their product at nutritional level. Also, the need of more personalized diets is an urgent requirement of EU healthcare systems,particularly for ageing and elderly people(EP).Nutraceuticals have different constraints not homogeneously defined in the EU Member States(MS)and their efficacy is always ...
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