5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Ubiquitous Pharmacogenomics (U-PGx): Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen (U-PGx)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Pharmacogenomics is the study of genetic variability affecting an individual’s response to a drug. Its use allows personalized medicine and reduction in ‘trial and error’ prescribing leading to more efficacious, safer and cost-effective drug therapy. The U-PGx consortium will investigate a pre-emptive genotyping approach (that is: multiple pharmacogenomic variants are collected prospectively and ...
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16
Participants partenaires
TERMINÉ
Point-of-care microfluidic device for quantification of chemotherapeutic drugs in small body fluid samples by highly selective nanoparticle extraction and liquid crystal detection (DiaChemo)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
The decision-making in chemotherapy nowadays depends on standard methods that are liquid chromatography (LC-MS/MS) followed by mass spectrometry or capillary electrophoresis; both are labour- and cost-intensive and can be performed only in dedicated hospitals and laboratories. This lead to a minimal therapeutic drug monitoring in patients and hence that 30-60% of drugs are administered without cli ...
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9
Participants partenaires
TERMINÉ
"Molecular Nanotechnology for Life Science Applications: QUantitative Interactomics for Diagnostics, PROteomics and QUantitative Oncology" (QUIDPROQUO)
Date du début: 1 juil. 2011, Date de fin: 30 juin 2016,
"The main goal of this proposal is to introduce innovative devices and protocols (based on nano- manipulation, the response of micro-(nano-)mechanical oscillators and nano-fluidics) to carry out, precise, high throughput, high sensitivity, and low cost interactomic measurements. We aim at measuring, in parallel, the concentration of up to several proteins or non-coding RNA molecules, in samples do ...
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2
Participants partenaires
TERMINÉ
Transposon based Forward Genetic Screen for the Identification of ncRNAs involved in Colorectal Cancer Metastasis (Transposon get ncRNA)
Date du début: 1 mars 2012, Date de fin: 11 août 2015,
In the era of target-based cancer therapies there is still missing a univocal hit for treating cancer metastatic spread, which is ultimately the main cause of cancer death. Non-protein-coding RNA transcripts (ncRNAs) were for long regarded as transcriptional noise; interestingly, it turns out that most of the genome does not carry protein-coding genes (PCGs) and yet is transcribed in a development ...
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1
Participant partenaire
TERMINÉ
Slovenian-Italian genetics network (SIGN)
Date du début: 31 oct. 2011, Date de fin: 30 oct. 2014,
Coordination between public health institutions and their cooperation with universities, as well as access to key experts in cross-border region Expected Results: The establishment of cross-border functional center in the fiel ...
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