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22 projets européens trouvés

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 TERMINÉ 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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 44

 TERMINÉ 

Diagnostic and Drug Discovery Initiative for Alzheimer’s Disease (D3i4AD)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2018,

Alzheimer’s disease (AD) is the major cause of dementia which has no cure at the moment. The overall aim of the work described in this proposal is to create a long-term strategic partnership between Sheffield University (UK), Lisbon University (Portugal), Eli Lilly (UK) and Biofordrug (Italy) in order to develop chemical biology tools for better understanding the role of PrPC in AD and harnessing ...
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 5

 TERMINÉ 

Quantifying Uncertainty in Integrated Catchment Studies (QUICS)

Date du début: 1 juin 2014, Date de fin: 31 mai 2018,

"The Water Framework Directive (WFD) is the most significant EU legislation concerning surface water management. Programs of Measures are required to ensure water bodies achieve a good ecological status. It is important to predict the impact of interventions on water quality. Man-made and natural processes control surface water quality, these are highly complex with a range of sources, transport a ...
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 10

 TERMINÉ 

Metal Hybrid Cavities (HyMeCav)

Date du début: 1 juin 2014, Date de fin: 31 janv. 2018,

Quantum semiconductor microcavities are structures in which photons can be confined within an area whose size is comparable to the wavelength of light. In this scenario, light-matter interactions can be substantially enhanced. A traditional microcavity is composed of two dielectric or semiconductor Bragg reflectors confining an active area which contains a quantum object such as a quantum well. F ...
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 7

 TERMINÉ 

The effect of intracoronary reinfusion of bone marrow-derived mononuclear cells (BM-MNC) on all-cause mortality in acute myocardial infarction (BAMI)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2017,

Although the long term prognosis of patients suffering acute myocardial infarction (AMI) has improved since the introduction of reperfusion therapies and primary angioplasty, the 1 year mortality of patients with AMI and resultant left ventricular systolic dysfunction (LVSD) is still as high as 13%. A major reason for the high morbidity and mortality is that the heart has an inadequate regenerativ ...
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 23

 TERMINÉ 

Advanced Immunization Technologies (ADITEC)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

 TERMINÉ 

Magnetic Resonance Imaging (MRI) and immunohistochemical investigations of CNS activity in a novel preclinical migraine model (MRIGRAINE)

Date du début: 1 janv. 2015, Date de fin: 6 mai 2017,

This application is being submitted by Dr Milena De Felice of the University of Arizona (researcher), and Professor Fiona Boissonade of the University of Sheffield (scientist-in-charge and supervisor), who have complementary expertise in different aspects of trigeminal pain. The project will be co-supervised by Dr Aneurin Kennerley, the lead physicist in the University of Sheffield's preclinical M ...
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 1

 TERMINÉ 

BeTheCuRE (BTCURE)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,

BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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 41

 TERMINÉ 

HYDRODYNAMIC TRANSPORT IN ECOLOGICALLY CRITICAL HETEROGENEOUS INTERFACES (HYTECH)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

Physical, biochemical and ecological processes in natural water bodies have been the subject of intense research over the past decades by scientists of different expertise. Environmental studies related to natural water bodies are a relatively new area of research, spanning over no more than fifty years. The dawning of environmental studies in the late 20th century has seen developments mainly con ...
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 11

 TERMINÉ 

Desistance from crime by restorative justice practices in prisons. A qualitative comparative research between the UK and Belgium (Desistance in prison)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2016,

Over the last fifteen years, proactive interest in Restorative Justice can clearly be observed at policy level within many European countries and within European institutions such as the Council of Europe and the European Union. While the implementation of restorative justice practices in Europe has essentially been victim-oriented, it is now increasingly focused on the moral and social rehabilita ...
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 1

 TERMINÉ 

Living with Hard Times: How European Citizens Deal with Economic Crises and Their Social and Political Consequences (LIVEWHAT)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2016,

The proposed research deals with citizens’ reactions to economic crises and their social and political consequences. It examines in particular the ways in which European citizens have reacted to the crisis that, at different degree of intensity in different countries, struck Europe since 2008, but also how they deal with economic crises and their consequences more generally. We examine both indivi ...
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 10

 TERMINÉ 

The Evolutionary Origins of Agriculture (EOA)

Date du début: 1 mai 2011, Date de fin: 31 janv. 2016,

The transition from a mobile hunter-gatherer lifestyle to one of settled agriculture is arguably the most fundamental change in human development since the origin of the human species, and the major question is why hunter-gatherer populations abandoned this way of life in favour of an agricultural existence. A crucial element in this change is the evolution of the crops upon which agriculture is f ...
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 2

 TERMINÉ 

Few Spin Solid-State Nano-systems (S^3NANO)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

"This network brings together an exceptionally strong group of world leading experts in nano-science and technology in order to achieve breakthroughs in understanding and successful utilisation of nanoscale systems in future devices. The focus of the consortium is on few spin nano-systems in solid-state materials including III-V semiconductors and Carbon-based structures: carbon nano-tubes, graphe ...
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 9

 TERMINÉ 

Europeana Creative

Date du début: 1 févr. 2013, Date de fin: 31 juil. 2015,

Europeana Creative will support and promote the re-use of cultural resources available via Europeana by realising a set of concrete objectives. (1) The project will establish the Europeana Labs Network of online and physical spaces for experimentation and engagement. The labs will provide access to technical and business services, and experimentation content to support the development of new proje ...
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 26

 TERMINÉ 

Suicidality: Treatment Occurring in Paediatrics (STOP)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2015,

The emergence of suicidality in patients receiving drug treatment is of concern because of the overall burden and the possible link with completed suicide. The lack of uniform requirements for defining, detecting and recording suicidality and the presence of disease related confounders create major problems. It is possible that Medication-Related Suicidality (MRS) differs from Psychopathology-Rela ...
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 19

 TERMINÉ 

Activation of vasculature associated stem cells and muscle stem cells for the repair and maintenance of muscle tissue (Endostem)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2014,

We propose to develop new strategies to mobilize skeletal muscle tissue-associated stem cells as a tool for efficient tissue repair. This will be combined with exploring novel approaches that limit tissue damage, and will focus on agents that modify muscle and muscle vasculature progenitor cells. These molecules include nitric oxide associated with non-steroidal anti-inflammatory drugs, HMGB1, Cri ...
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 22

 TERMINÉ 

Development of OPN-305 as an orphan drug for the treatment of Delayed Graft Function post solid organ transplantation (MABSOT)

Date du début: 1 déc. 2010, Date de fin: 30 sept. 2014,

Delayed graft function (DGF) is defined as the need for dialysis within seven days of renal transplantation (DGF promotes allograft rejection, requires prolonged dialysis and hospitalisation, and increases the likelihood of graft failure and ultimately the duration of renal graft survival-expectancy. The incidence of DGF occurs in 21-44% of cases following cadaveric renal graft. Several rare dise ...
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 10

 TERMINÉ 

Enhancing European Coordination for National Research Programmes in the Area of Security at Major Events (THE HOUSE)

Date du début: 1 mars 2012, Date de fin: 31 mai 2014,

"Enhancing European Coordination for National Research Programmes in the Area of Security at Major Events – THE HOUSE is aimed at strengthening the ERA on Major Events security by applying the research coordination tools/methodologies developed during seven years of activity within the projects EU-SEC and EU-SEC II. THE HOUSE builds on the assumption that Major Events are “windows of opportunity” ...
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 25

 TERMINÉ 

Translational research in human epilepsies (TRHE)

Date du début: 1 mars 2010, Date de fin: 28 févr. 2014,

"The goal of this proposal is to identify the major genes and gene variants that cause human epilepsies and their comorbid traits of cognitive and behavioral impairments. The common epilepsies are complex disorders caused by a combination of susceptibility genes. To date we have identified major genes for three main classes of epilepsy that account for 30% of the population total. In this proposal ...
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 1

 TERMINÉ 

European Network for Cell Imaging and Tracking Expertise (ENCITE)

Date du début: 1 juin 2008, Date de fin: 30 nov. 2012,

"Cell therapy can be defined as the transplantation of living cells for the treatment of medical disorders. Three different principles underlie the increasing interest in cell therapy. 1. Transplanted cells used as an “active drug” 2. Transplanted cells used to replace damaged and degenerated tissue. 3. Cells used as a drug delivery vehicle. Promising results have been obtained in pre-clinical and ...
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 30

 TERMINÉ 

SCIENTIFIC INDICATORS OF CONFIDENCE IN JUSTICE: TOOLS FOR POLICY ASSESSMENT (EURO-JUSTIS)

Date du début: 1 mars 2008, Date de fin: 30 juin 2011,

"EURO-JUSTIS (Justice Indicators) is a project designed to provide EU institutions and Member States with new indicators for assessing public confidence in justice. Member States are making growing use of social indicators to improve policy and its assessment, but limited progress has been made in criminal justice. Common-sense indicators based on readily available statistics – such as crime trend ...
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 10

 TERMINÉ 

The zona limitans intrathalamica as an organiser of diencephalic development (ZLIDIDE)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2010,

The generation of the vertebrate brain relies on regionalisation of the neural plate through formation of boundaries. An important function of boundaries is to maintain the position of special groups of cells that are able to direct development of the neighbouring tissue. Such cell types form organisers and exert their action through secretion of long range signalling molecules. The formation of b ...
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 1