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 TERMINÉ 
DESIRE will focus on epileptogenic developmental disorders EDD, i.e. early onset epilepsies whose origin is closely related to developmental brain processes. A major cause of EDD are malformations of cortical development (MCD), either macroscopic or subtle. EDD are often manifested as epileptic encephalopathies (EE), i.e. conditions in which epileptic activity itself may contribute to severe cogni ...
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 29

 TERMINÉ 
"The objective of this project is to overcome current limitations for antibody production that are inherent to the extant immune system of vertebrates. This will be done by creating an all-in-one artificial/synthetic counterpart based exclusively on prokaryotic parts, devices and modules. To this end, ARISYS will exploit design concepts, construction hierarchies and standardization notions that st ...
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 1

 TERMINÉ 
"The majority of animals show an external bilateral symmetry, precluding the observation of multiple internal left-right (L/R) asymmetries which are fundamental for organ packaging and function. A prominent molecular pathway converging on and downstream of the Pitx2 transcription factor confers left-handed information in the left side of the embryo, with players expressed on the right ensuring tha ...
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 1

 TERMINÉ 
"In an early sixteenth-century treatise Martín de Figuerola, a convert from Islam who sought to convince the Muslims of Valencia and Aragon to join him, reports a story he claims to have heard from the Muslim judge of Cocentaina (Valencia). The latter had told him that, in marriage contracts between local Muslims, it was customary for women to demand that their husbands take them to the capital ci ...
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 1

 TERMINÉ 

Probing Strong Gravity by Black Holes Across the Range of Masses (StrongGravity)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

Black holes provide a crucial link between Einstein’s theory of gravity and real cosmic objects which astronomers can observe and study in the Universe. This project is oriented towards legacy of the cornerstone XMM-Newton X-ray satellite mission of European Space Agency (ESA) in synergy with relevant data in other spectral domains that are covered by ground-based infrared and radio interferometri ...
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 7

 TERMINÉ 

Operational Potential of Ecosystem Research Applications (OPERAs)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,

Human use and exploitation of the biosphere is increasing at such a pace and scale that the sustainability of major ecosystems is threatened, and may not be able to continue to function in ways that are vital to the existence of humanity. Re-framing environmental resource use has led to the emergence of the concepts of ecosystem services (ES) and natural capital (NC). This discourse indicates not ...
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 27

 TERMINÉ 
"TRUST aims at conducting CO2 injection experiments at scales large enough so that the output can be extrapolated at industrial scales. It relies on four sites: the heavily instrumented sites of Heletz (Israel, main site) and Hontomin (Spain), access Miranga (Brazil) and the emerging site in the Baltic Sea region. The objectives are to: carry out CO2 injection with different strategies, displaying ...
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 18

 TERMINÉ 
The neural assembly underlying the formation of functional networks in the cerebral cortex is conceivably the most complex biological system that exists. Much of this complexity arises during development through the interaction of dozens of different neuronal populations, which belong to two general classes: excitatory glutamatergic pyramidal cells and inhibitory gamma-aminobutyric containing (GA ...
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 3

 TERMINÉ 
EURenOmics will integrate several established consortia devoted to rare kidney diseases with eminent need and potential for diagnostic and therapeutic progress (i.e. steroid resistant nephrotic syndrome, membranous nephropathy, tubulopathies, complement disorders such a haemolytic uraemic syndrome, and congenital kidney malformations). The Consortium has access to the largest clinical cohorts asse ...
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 29

 TERMINÉ 

Synthesis of systematic resources (SYNTHESYS3)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

SYNTHESYS3 will create an accessible, integrated European resource for researchers in the natural sciences in Europe and globally. Building on the success of the previous SYNTHESYS IA, the NA will focus on improving collections management of new physical and virtual collections. By focusing the JRA on extracting and enhancing data from digitised collections, SYNTHESYS3 will increase the accessibil ...
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 21

 TERMINÉ 

Mediterranean Science, Policy, Research & Innovation Gateway (MED-SPRING)

Date du début: 1 févr. 2013, Date de fin: 31 juil. 2017,

The main aim of the Project is to contribute to the quality of the Euro-Mediterranean research area, with a particular focus on the bi-regional Euro-Mediterranean S&T cooperation, research & innovation, policy dialogue and cooperation monitoring. The proposal aims at tackling the key issues and policy objectives outlined in the Work Programme by creating a dialogue and coordination platform of gov ...
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 28

 TERMINÉ 

EU BON: Building the European Biodiversity Observation Network (EU BON)

Date du début: 1 déc. 2012, Date de fin: 31 mai 2017,

Sustainable governance of our biological resources requires reliable scientific knowledge that meets the needs of society. Current biodiversity observation systems and environmental datasets are unbalanced in coverage and not integrated, limiting integrative analyses and implementation of environmental policies.EU BON presents an innovative approach towards integration of biodiversity information ...
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 32

 TERMINÉ 

Enhanced European Coordination for Accelerator Research & Development (EUCARD-2)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

Research accelerators are facing important challenges that must be addressed in the years to come: existing infrastructures are stretched to all performance frontiers, new world-class facilities on the ESFRI roadmap are starting or nearing completion, and strategic decisions are needed for future accelerators and major upgrades in Europe.While current projects concentrate on their specific objecti ...
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 40

 TERMINÉ 
"Extensive clinical and epidemiological data clearly shows that chronic periodontal disease (PD), the most prevalent infectious inflammatory disease of mankind, is strongly linked to systemic inflammatory diseases such as cardiovascular diseases (CVD) , rheumatoid arthritis (RA) , and chronic obstructive pulmonary disease (COPD) . Taking into account that up to 30% of the adult population worldwid ...
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 11

 TERMINÉ 
"HOMIN is designed as an advanced education and research program meant to train junior investigators possessing medical and/or scientific educational backgrounds to become future leading scientists in academic institutions, private companies, or administration.The HOMIN objectives are:1. To provide multidisciplinary and intersectorial scientific education through the study of host-microbe interact ...
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 5

 TERMINÉ 

High-Resolution Solar Physics Network (SOLARNET)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

This project aims at integrating the major European infrastructures in the field of high-resolution solar physics. The following actions will be taken: (i) realise Trans-national Access to external European users; (ii) enhance and spread data acquisition and processing expertise to the Europe-wide community; (iii) increase the impact of high-resolution data by offering science-ready data and facil ...
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 32

 TERMINÉ 
The aim of the project is to develop a completely new manufacturing system for the volume production of miniaturised components by overcoming the challenges on the manufacturing with a wide range of materials (metallic alloys, composites, ceramics and polymers), through: (i) developing a high-throughput, flexible and cost-efficient process by simultaneous electrical-forming and electric-fast-sinte ...
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 17

 TERMINÉ 

New operational steps towards an alliance of European research fleets (EUROFLEETS2)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

EUROFLEETS2 is the enhancement of EUROFLEETS1, with the aim of developing a new pan-European distributed infrastructure with common strategic vision and coordinated access to Research Vessels (RVs) and marine equipment. EUROFLEETS2 will furthermore undertake specific actions to consolidate research fleets’ organization, methodology and tools through operational initiatives (like virtual fleets) le ...
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 32

 TERMINÉ 

Autonomous Paper-based Point-of-Care Biosensing System (APPOCS)

Date du début: 16 août 2013, Date de fin: 15 févr. 2017,

The objective of this proposal is the development of a fuel cell powered point-of-care analytical device based on paper microfluidics. The device would comprise a power source, biosensors, electronics module and display, to allow the autonomous quantitative measurement of a biological sample and visualize the results within a thin, flexible and disposable package. A first phase of the project (out ...
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 1

 TERMINÉ 
The World Meteorological Organization (WMO) sponsored the Global Framework on Climate Services (GFCS) where the need for actionable climate information for periods from several months up to several years for economic, industrial and political planning has been expressed. However, progress in seasonal forecasting has been slow and decadal forecasting is still incipient. At the same time, new model ...
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 21

 TERMINÉ 
The main objectives of this project are to investigate the diversity of family forms, relationships, and life courses in Europe; to assess the compatibility of existing policies with these changes; and to contribute to evidence-based policy-making. The project will extend our knowledge on how policies promote well-being, inclusion and sustainable societal development among families. Our approach r ...
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 29

 TERMINÉ 
The proposed European-US and South American network IMCONet will advance climate and (eco-) system change research at the Western Antarctic Peninsula (WAP), a region of recent rapid aerial warming. WAP glaciers contribute to global sea level rise, and functioning and services of coastal ecosystems are massively threatened by the fast regional warming. Data sets from recent interdisciplinary Europe ...
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 8

 TERMINÉ 
ARIADNE is a proposal to bring together and integrate the existing archaeological research data infrastructures so that researchers can use the various distributed datasets and new and powerful technologies as an integral component of the archaeological research methodology. There is now a large availability of archaeological digital datasets that altogether span different periods, domains and reg ...
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 24

 TERMINÉ 
Chronic inflammation and dysregulation of the immune response underlie multiple human pathologies, including rheumatoid arthritis and systemic lupus erythematosus. Autoimmune disorders comprise more that 50 distinct diseases and affect about 5% of the population in Europe. Thus, chronic inflammation and autoimmunity are one of the thematic priorities within FP7 Cooperation Health (‘Other Chronic D ...
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 1

 TERMINÉ 

Human EXposure to Aerosol Contaminants in Modern Microenvironments (HEXACOMM)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"The main research goal of HEXACOMM is to apply scientifically-based modelling and experimental methods to relate concentrations of particulate matter in the indoor domestic environment to its sources and human exposure implications. The second research objective is to determine the human exposure arising from such exposure at both individual and collective (population) scales at modern microenvir ...
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 10

 TERMINÉ 
"Coral reefs are home to the greatest density of species in shallow marine waters, including unusually diverse microbial communities. However, almost everything we know about reef microbial communities is confined to prokaryotes and viruses: next to nothing is known about the microbial eukaryotes, with the exception of the symbiont dinoflagellate Symbiodinium. Coral reefs are like most other marin ...
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 1

 TERMINÉ 
"During the last decades, artificial lighting have been increasing at a rate of 6% the World, increasing the light pollution levels. Currently, lighting constitutes the 16% of global electricity. The European Ecodesign Directive established a framework to phase out particularly energy-intensive lights. Until now, economic and energetic optimization has solely driven eco-friendly lighting strategie ...
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 1

 TERMINÉ 

Passive and Active Systems on Severe Accident source term Mitigation (PASSAM)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"In case of a severe accident in a Nuclear Power Plant (NPP) fission products are released from the degraded fuel and might reach the environment if their confinement is lost and/or bypassed. Given the high radio-toxic nature of fission products for environment and population, their release should be avoided at all costs. This highlights the importance of relying on efficient mitigation systems ca ...
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 11

 TERMINÉ 

Optical Infrared Co-ordination Network for Astronomy (OPTICON)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

Optical-infrared astronomy in Europe is in a state of transition and opportunity, with the goal of a viable structured European scale community in sight. A strong astronomical community requires access to state of the art infrastructures (telescopes), equipped with the best possible instrumentation, and with that access being open to all on a basis of competitive excellence. Further, the community ...
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 26

 TERMINÉ 

Exploitation of Space Data for Innovative Helio- and Asteroseismology (SPACEINN)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

Observations of oscillations on the solar and stellar surfaces have emerged as a unique and extremely powerful tool to gain information on, and understanding of, the processes in the Sun and stars, and the origin of the variability in the solar and stellar output.Through helio- and asteroseismology detailed inferences of the internal structure and rotation of the Sun, and extensive information on ...
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 17

 TERMINÉ 
"PIMIC is a cooperative effort by a team of western medievalists, Arabists and Byzantinists -eight partners from prestigious academic institutions and two private sector companies- in order to propose a four years ITN program. For this project, we will take advantage of the wide-ranging expertise and complementarities of all ITN partners, composed of some of the most relevant research in mediaeval ...
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 11

 TERMINÉ 

Integrated Biotechnological Solutions for Combating Marine Oil Spills (Kill●Spill)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

Kill●Spill delivers innovative (bio)technologies, which can be integrated to the real sequences of state-of-the-art actions used currently to cleanup oil spills. The catalogue of Kill●Spill products & technologies is based on a review of technology & knowledge gaps in approaches of oil spill disasters and brings appropriate tools for 1st response, follow-up, and longer-term actions, specifically t ...
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 35

 TERMINÉ 
The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:• Develop a series of mutant alleles for every gene in the mouse genome• Determine the phenotypic consequences of each mutation• Identify mouse models for the complete dise ...
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 24

 TERMINÉ 
"The strategic goal of the project is to help the European vineyard sector facing the increasingly global competition by meeting:* Consumer demands for diversified high quality wines and concerns for food safety* Citizens’ requests for environment-friendly production systems involving decreased or no use of pesticides and spare of not renewable natural resources* Producers’ needs of plant material ...
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 29

 TERMINÉ 

Urban musics and musical practices in sixteenth-century Europe (URBANMUSICS)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2016,

"The urban musics and musical practices of sixteenth-century European cities have been studied only rather patchily in terms of geography and partially in terms of urban culture. Renaissance Italian cities, benefiting from a strong cultural historical tradition, have fared relatively well, while music in the urban context in France, Flanders, Germany and England has been considered in a steady tri ...
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 1

 TERMINÉ 
The objectives are to:(i) improve our understanding of human activities impacts (cumulative, synergistic, antagonistic) and variations due to climate change on marine biodiversity, using long-term series (pelagic and benthic). This objective will identify the barriers and bottlenecks (socio-economic and legislative) that prevent the GES being achieved(ii) test the indicators proposed by the EC, an ...
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 25

 TERMINÉ 
From chloride to DNA, over 75% of the cofactors and bio-molecules have negative charge at physiological pH. However, efficient syntheticreceptors for anionic entities in aqueous solution have attracted lesser attention than ligands for cationic or neutral species. The intrinsicphysicochemical problems of anion binding and the molecular diversity of anionic species have often hampered this research ...
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 1

 TERMINÉ 

Multistage Logic Platforms (MuLoPla)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

Microfluidic technologies offer significant advantages in crystal growth design and guided assembly when compared to conventional synthetic methods. For this reason, the motivation of the present project will be leaded to construct microfluidic platforms, hereafter called Multistage Logic Platforms (MuLoPla), where site-specific crystal growth, different patterns, and multiple template assemblies ...
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 1

 TERMINÉ 
"The main objective of the BACCHUS project is to develop tools and resources that will facilitate the generation of robust and exploitable scientific evidence that can be used to support claims of a cause and effect relationship between consumption of bioactive peptides and polyphenols, and beneficial physiological effects related to cardiovascular health in humans. To achieve this, the BACCHUS c ...
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 28

 TERMINÉ 

Biopolymers from syngas fermentation (SYNPOL)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

"SYNPOL aims to propel the sustainable production of new biopolymers from feedstock. SYNPOL will thereto establish a platform that integrates biopolymer production through modern processing technologies, with bacterial fermentation of syngas, and the pyrolysis of highly complex biowaste (e.g., municipal, commercial, sludge, agricultural). The R&D activities will focus on the integration of innovat ...
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 16