4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Developing new therapies for Batten disease (BATCure)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,
The goal of BATCure is to advance the development of new therapeutic options for a group of rare lysosomal diseases - neuronal ceroid lipofuscinoses (NCL) or Batten disease. There are > thousand affected across Europe, with a combined incidence of c.1:100 000. The NCLs are devastating and debilitating genetic disorders that mainly affect children, who suffer progressive dementia and motor decline, ...
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14
Participants partenaires
TERMINÉ
"Health and the Understanding of Metabolism, Aging and Nutrition" (HUMAN)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
"Recently intense research identified around 4,000 single nucleotide polymorphisms (SNPs) associated with human age related diseases such as metabolic disorders. Despite their highly significant association to pathology, the functional role of these genetic variants is, in most cases, yet to be elucidated. The evolutionary distance of most animal models from humans represents a major limitation fo ...
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17
Participants partenaires
TERMINÉ
Biomarkers of renal graft injuries in kidney allograft recipients (BIOMARGIN)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,
In renal allograft recipients, 10-year graft survival has not improved over the past decades. Histological examination of graft biopsies has long been the gold standard to confirm graft injuries, but biopsies are invasive and histological grading is not very robust. There is thus a need for robust, non-invasive methods to predict and diagnose acute and chronic graft lesions, to improve patient tre ...
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13
Participants partenaires
TERMINÉ
Biology of Liver and Pancreatic Development and Disease (BOLD)
Date du début: 1 sept. 2009, Date de fin: 31 août 2013,
Aims: provide a cutting edge research training programme encompassing complementary approaches to the investigation of liver and pancreatic development and disease. Provide early stage researchers with a balanced mix of experience and skills in academic and industry based research. Give early stage researchers a set of transferrable skills which will improve their employment and career prospects. ...
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