4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
A multi-center randomized, placebo-controlled trial of mirabegron, a new beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease (BETA3_LVH)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Patients with cardiovascular risk factors, e.g. hypertension and obesity are at risk of developing heart failure with preserved ejection fraction (HFpEF), a highly prevalent disease in the elderly, mostly women population. There is currently no specific, defined treatment for HFpEF, beyond control of risk factors. Activation of cardiac and vascular Beta3-adrenergic receptors (B3AR) represents a ne ...
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15
Participants partenaires
TERMINÉ
Novel Stromal Cell Therapy for Diabetic Kidney Disease (NEPHSTROM)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
Type 2 diabetes will affect >500 million adults by 2040 and its secondary complications will generate enormous socioeconomic costs - in particular, diabetic kidney disease (DKD), which is already the most common cause of chronic kidney disease. DKD is associated with greatly increased mortality and frequently progresses to end stage renal failure. Pharmacotherapy, dialysis and transplantation repr ...
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12
Participants partenaires
TERMINÉ
Stem-cell based therapy for kidney repair (STELLAR)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
Chronic kidney disease (CKD) affects 8% of the European population and ultimately results in renal failure due to progressive fibrosis. CDK carries a high mortality risk and the number of affected people rises, increasing the demand on renal replacement therapies while the number of available donor organs stays stable.The STELLAR consortium proposes to develop an alternative to renal replacement ...
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15
Participants partenaires
TERMINÉ
PREvention of Late Stent Thrombosis by an Interdisciplinary Global European effort (PRESTIGE)
Date du début: 1 déc. 2010, Date de fin: 30 nov. 2014,
"According to the European Society of Cardiology there has been an increase in the life expectancy at the age of 65 of the European population from 15.0 to 17.0 years in the years since 1980. In the elderly, up to 50% of deaths are caused by cardiovascular diseases, the majority accounted for by coronary artery disease. The most effective treatment for obstructive coronary disease is percutaneous ...
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