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 TERMINÉ 

A Systems medicine approach to chronic inflammatory disease (SYSCID)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2022,

"The SYSCID consortium aims to develop a systems medicine approach for disease prediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, Twins ...
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 16

 TERMINÉ 

GALAXY: Gut-and-liver axis in alcoholic liver fibrosis (GALAXY)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2021,

Alcohol overuse is an important societal challenge with annual healthcare costs of over €22 billion in Europe. Alcohol is the main cause of liver cirrhosis, which is the 5th and 7th most common cause of life years lost in respectively Eastern and Western Europe. Cirrhosis is considered irreversible but its precursor, liver fibrosis, is reversible when detected before disease progression. GALAXY pr ...
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 12

 TERMINÉ 

The European network for observing our changing planet (ERA-PLANET)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2021,

In the last decade a significant number of projects and programmes in different domains of environmental monitoring and Earth observation have generated a substantial amount of data and knowledge on different aspects related to environmental quality and sustainability. Big data generated by in-situ or satellite platforms are being collected and archived with a plethora of systems and instruments m ...
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 38

 TERMINÉ 

Translational Research Network in Prostate Cancer (TransPot)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The Translational Research Network for Prostate Cancer (TransPot) program adopts an innovative, multidisciplinary approach, providing highly sought-after, effective solutions for incurable prostate cancer (PC).The TransPot scientific objective is to obtain an unmatched depth of molecular, mechanistic and informatics systems-level disease understanding in order to improve the prognosis and treatmen ...
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 11

 TERMINÉ 

Big data against childhood Obesity (BigO)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

Childhood and adolescent obesity is a major global and European public health problem. Currently, public actions are detached from local needs, mostly including indiscriminate blanket policies and single-element strategies, limiting their efficacy and effectiveness. The need for community-targeted actions has long been obvious, but the lack of monitoring and evaluation framework and the methodolog ...
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 14

 TERMINÉ 

Innovative approaches to turn agricultural waste into ecological and economic assets (NoAW)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

NoAW : No Agro-Waste.Innovative approaches to turn agricultural waste into ecological and economic assets.Driven by a “near zero-waste” society requirement, the goal of NoAW project is to generate innovative efficient approaches to convert growing agricultural waste issues into eco-efficient bio-based products opportunities with direct benefits for both environment, economy and EU consumer. To ach ...
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 32

 TERMINÉ 

Interactive Soil Quality Assessment in Europe and China for Agricultural Productivity and Environmental Resilience (iSQAPER)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

Knowledge regarding the complex interplay between agricultural land use and management and soil quality and function is fragmented and incomplete, in particular with regard to underlying principles and regulating mechanisms. The main aim of iSQAPER is to develop an interactive soil quality assessment tool (SQAPP) for agricultural land users that integrates newly derived process understanding and a ...
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 25

 TERMINÉ 

ACTRIS PPP - Aerosols, Clouds and Trace gases Preparatory Phase Project (ACTRIS PPP)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

The Research Infrastructure (RI) ACTRIS – Aerosols, Clouds and Trace Gases - is the pan-European RI that consolidates activities amongst European partners for observations of aerosols, clouds, and trace gases and for understanding of the related atmospheric processes, to provide RI services to wide user groups. ACTRIS is composed of 8 connected elements: distributed National Facilities (observatio ...
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 28

 TERMINÉ 

A miniature Bio-photonics Companion Diagnostics platform for reliable cancer diagnosis and treatment monitoring. (BIOCDx)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

Current diagnostic options for cancer treatment monitoring rely on imaging techniques and cannot guarantee proper assessment of therapeutic response. This project aims to develop a disruptive Point of Care (PoC) device for cancer early diagnosis and treatment monitoring as a companion diagnostics tool. One of the scientific breakthroughs of this project is the development of a “cancer stem cells” ...
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 8

 TERMINÉ 

PRoteome-based assessment of vascular disease for the Establishment of a Translational REsearch plATform (PRETREAT)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Cardiovascular disease (VD) is the leading cause of mortality and morbidity in Europe and worldwide. The objective of the PRETREAT consortium is to generate a joint SME/academic European preclinical platform for providing services for detection of VD and drug development. This platform will combine the use of urinary and/or blood peptidomics in humans and in preclinical animal models of VD, togeth ...
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 6

 TERMINÉ 

Coordinated Research Infrastructures Building Enduring Life-science services (CORBEL)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

The social and economic challenges of ageing populations and chronic disease can only be met by translation of biomedical discoveries to new, innovative and cost effective treatments. The ESFRI Biological and Medical Research Infrastructures (BMS RI) underpin every step in this process; effectively joining scientific capabilities and shared services will transform the understanding of biological m ...
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 39

 TERMINÉ 

Pooling Activities, Resources and Tools for Heritage E-research Networking, Optimization and Synergies (PARTHENOS)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

PARTHENOS aims at strengthening the cohesion of research in the broad sector of Linguistic Studies, Humanities, Cultural Heritage, History, Archaeology and related fields through a thematic cluster of European Research Infrastructures, integrating initiatives, e-infrastructures and other world-class infrastructures, and building bridges between different, although tightly, interrelated fields. PAR ...
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 19

 TERMINÉ 

Aerosols, Clouds, and Trace gases Research InfraStructure (ACTRIS-2)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

ACTRIS-2 addresses the scope of integrating state-of-the-art European ground-based stations for long term observations of aerosols, clouds and short lived gases capitalizing work of FP7-ACTRIS. ACTRIS-2 aims to achieve the construction of a user-oriented RI, unique in the EU-RI landscape. ACTRIS-2 provides 4-D integrated high-quality data from near-surface to high altitude (vertical profiles and t ...
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 32

 TERMINÉ 

implementAtion anD OPeration of the gateway for healTh into BBMRI-ERIC (ADOPT BBMRI-ERIC)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2018,

"BBMRI-ERIC: the Biobanking and BioMolecular resources Research Infrastructure - European Research Infrastructure Consortium, aims to establish, operate and develop a Pan-European distributed research infrastructure in order to facilitate the access to biological resources as well as facilities and to support high quality biomolecular and biomedical research. The ADOPT BBMRI-ERIC proposal aims at ...
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 22

 TERMINÉ 

Multimodal Imaging of rare Synucleinopathies (MultISyn)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Despite remarkable progress in the understanding of the molecular pathogenesis of neurodegenerative diseases (NDD), no causative or disease-modifying treatment is currently available. Aggregation of misfolded proteins are thought to play a crucial role in the pathogenesis, but attempts to exploit this knowledge for novel treatments have not been successful. Also, pathogenetically relevant biomarke ...
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 9

 TERMINÉ 

Targeting novel lipid pathways for treatment of cardiovascular disease (Athero-Flux)

Date du début: 1 sept. 2013, Date de fin: 31 août 2018,

Lipid lowering has significantly reduced cardiovascular disease (CVD) mortality in EU. However, the aim to abolish CVD in EU is far from achieved and attempts to improve on the benefits of statins with new agents have not yet delivered new therapeutics. The Consortium Athero-Flux builds on FP7-generated large-scale lipidomics data showing that specific sphingolipids and in particular distinct cer ...
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 12

 TERMINÉ 

Coordinating and integRating state-of-the-art Earth Observation Activities in the regions of North Africa, Middle East, and Balkans and Developing Links with GEO related initiatives towards GEOSS (GEO-CRADLE)

Date du début: 1 févr. 2016, Date de fin: 31 juil. 2018,

GEO-CRADLE brings together key players representing the whole (Balkans, N. Africa and M. East) region and the complete EO value chain with the overarching objective of establishing a multi-regional coordination network that will (i) support the effective integration of existing EO capacities (space/air-borne/in-situ monitoring networks, modelling and data exploitation skills, and past project expe ...
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 20

 TERMINÉ 

Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

 TERMINÉ 

Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
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 19

 TERMINÉ 

Transferring NOn autonomous cell degeneration models between EU and USA for development of effective therapies for Motor Neuron Diseases (MND) (NO-MND)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

"Amyotrophic lateral sclerosis (ALS) and Spinal Muscular Atrophy (SMA) are fatal diseases characterized by selective degeneration of motor neurons without any effective treatment. Non-neuronal cells like astrocytes play a key role in the pathogenesis of ALS and SMA. Understanding the mechanisms of cell death caused by non-neuronal cells is a major research target and it has been proposed that tran ...
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 3

 TERMINÉ 

Flare Likelihood and Region Eruption Forecasting (FLARECAST)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2017,

Space weather can have detrimental, and in some cases catastrophic, effects upon a multitude of technologies on which we depend as part our daily lives. Adverse space weather is now known to result from solar flares and coronal mass ejections released from the turbulent and highly complex magnetic fields of active regions. Understanding how active region magnetic fields evolve and produce these ev ...
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 9

 TERMINÉ 

Fuctionalised Innovative Carbon Fibres Developed from Novel Precursors With Cost Efficiency and Tailored Properties (FIBRALSPEC)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"Innovative processes with streamlining and improved control will be conducted in FIBRALSPEC, through Unit for Continuous PAN-based Carbon Fiber Pilot Production. Testing of laminates and prepregs production based the new developed carbon fibres followed by manufacturing of laminates/coupons and high-performance filament wound tubes are also foreseen (equipment for delivering precise volumes the m ...
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 11

 TERMINÉ 

Personalized diagnostics and treatment of high risk coronary artery disease patients (RISKYCAD)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

Although the accurate diagnosis and prevention of coronary artery disease (CAD), acute myocardial infarction (AMI) and death is a major public health issue, risk stratification for CAD with current diagnostic tools is not properly supporting clinical decision making. RiskyCAD’s overall goal is to identify novel biomarkers for asymptomatic patients in high risk of major coronary events, and develop ...
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 12

 TERMINÉ 

Clinical and system –omics for the identification of the MOlecular DEterminants of established Chronic Kidney Disease (iMODE-CKD)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

iMODE-CKD integrates multi-disciplinary expertise in proteomics, metabolomics, transcriptomics, bioinformatics, pathology, and clinical science from leading academic and industrial investigators, establishing a unique training platform on biomarker research and Systems Biology. Special emphasis is placed on the application of a wide range of –omics and bioinformatics techniques to clinical researc ...
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 10

 TERMINÉ 

Monitoring and Assessment of Regional air quality in China using space Observations, Project Of Long-term sino-european co-Operation (MARCOPOLO)

Date du début: 27 sept. 2013, Date de fin: 1 avr. 2017,

Due to the strong economic growth in the China in the past decade, air pollution has become a serious issue in many parts of the country. Therefore, up-to-date regional air pollution information and means of emission control for the main pollutants are important for China. Especially, the Beijing-Tianjin-Hebei region, the Yangtze River and the Pearl River deltas are known as three focal regions wi ...
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 15

 TERMINÉ 

BeTheCuRE (BTCURE)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,

BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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 41

 TERMINÉ 

NOX enzymes as mediators of inflammation-triggered neurodegeneration: modulating NOX enzymes as novel therapies (NEURINOX)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

NEURINOX aims at elucidating the role of NADPH oxidases (NOX) in neuroinflammation and its progression to neurodegenerative diseases (ND), as well as evaluating the potential of novel ND therapeutics approaches targeting NOX activity. NOX generate reactive oxygen species (ROS) and have emerged as regulators of neuroinflammation. Their role is complex: ROS generated by NOX lead to tissue damage in ...
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 15

 TERMINÉ 

THALAssaemia MOdular Stratification System for personalized therapy of beta-thalassemia (THALAMOSS)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,

...thous (The Cyprus Foundation for Muscular Dystrophy Research, Cyprus), S.Philipsen (Erasmus Universitair Medisch Centrum Rotterdam, The Netherlands), E.Katsantoni (Biomedical Research Foundation, Academy of Athens, Greece), S.Rivella (Cornell University, NY, USA - The Children's Hospital of Philadelphia, Philadelphia, USA), P.Holub (Masaryk University, Czech Republic), P. Moi (Cagliari University ...
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 14

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

Molecular Medicine for Bladder Cancer (BCMolMed)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

BCMolMed integrates complementary and multi-disciplinary expertise of two main (research-intensive SME-academia) and five associate partners with the objective to generate a state of the art training platform on application-oriented biomarker research and systems biology. Special emphasis is placed on the efficient employment of proteomics and bioinformatics techniques to clinical research, and un ...
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 3

 TERMINÉ 

Translation of novel Biomarkers for Bladder Cancer for clinical outcome prediction (TransBioBC)

Date du début: 1 sept. 2013, Date de fin: 31 août 2016,

Currently, clinical diagnosis and monitoring of bladder cancer (BC) relies on invasive, highly costly cystoscopy. Additionally, due to high recurrence rates BC treatment is associated with frequent follow-up of patients, making BC one of the most costly types of cancer in terms of management cost. Thus there is a clear clinical need for the development of new approaches for early detection of recu ...
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 5

 TERMINÉ 

Fostering Dialogue and Cooperation between the EU and EECA in the HORIZON 2020 perspective (EAST-HORIZON)

Date du début: 1 févr. 2014, Date de fin: 31 juil. 2016,

In the fluid environment of the junction between FP7 and HORIZON 2020, the EAST HORIZON Support Action, brought forward by a balanced mixture of European Strategic Consulting companies, IT Industry, EECA National Research and Governmental Organizations, comes as a bridge for a two-way cooperation between the EECA and the EU.It will inspire ideas, influence policies, and launch actions to:Support t ...
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 14

 TERMINÉ 

A Gateway to European Kidney Research Resources - KidneyConnect (KidneyConnect)

Date du début: 1 août 2013, Date de fin: 31 juil. 2016,

Diabetes, Cardiovascular and Chronic kidney (DCC) -diseases are relentlessly increasing globally, causing enormous human suffering, premature deaths and unsustainable costs. Leading European research has indisputably pointed that the kidney filtration barrier and its epithelial cell, the podocyte, is a common denominator for the DCC-diseases. However, European excellence and expertise have remaine ...
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 19

 TERMINÉ 

PROMOTING ICT DIALOGUE AND COOPERATION WITH THE MPC TOWARDS HORIZON 2020 (MED-Dialogue)

Date du début: 1 janv. 2014, Date de fin: 30 juin 2016,

In line with the new concept in Horizon 2020 which integrates industrial cooperation and innovation, and the need to go beyond the old "extended workbench" principle, two are the most important aspects of such ex-tension:1) to incorporate ETPs2) to increase the participation of innovation driven SMEs from both sides.In this transition between FP7 ending and the launch of HORIZON 2020, comes the ME ...
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 12

 TERMINÉ 

Post-infectious immune reprogramming and its association with persistence and chronicity of respiratory allergic diseases (PreDicta)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2016,

Chronic inflammatory diseases associated with allergy, including asthma and rhinitis, constitute a major and continuously growing public health concern for Europe. However, the causative factors and mechanisms converting a physiological inflammatory reaction to a chronic response triggering allergic disease remain elusive.Viral infections, particularly those caused by human rhinoviruses (RV) are t ...
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 13

 TERMINÉ 

hERG related risk assessment of botanicals (HERGSCREEN)

Date du début: 1 mars 2012, Date de fin: 29 févr. 2016,

The main goal of this project is the establishment of a network between European, South American, North American and South African educational and research entities. This attempt will be based on an innovative scientific project aiming towards the identification of hERG (human Ether-à-go-go Related Gene) channel blockers in commonly consumed botanicals and supplements. Blocking these ion channels ...
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 6

 TERMINÉ 

Small scale thermal solar district units for Mediterranean communities (STS-Med)

Date du début: 16 nov. 2012, Date de fin: 30 déc. 2015,

The project in brief In the Mediterranean area, a large share of energy is consumed by households and in buildings. In addition to the dependence on fossil fuel, oil and natural gas, the primary energy demand is growing at a regular pace. Increasing the share of solar energy sources in the overall energy mix is a crucial goal for the Mediterranean area, as the exploitation of a sustainable renewab ...
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 14

 TERMINÉ 

Immune mechanisms of osteopontin-mediated protection in allergic airway disease (OPN-IMMUNOREGULATION)

Date du début: 1 déc. 2009, Date de fin: 30 nov. 2015,

In allergic asthma, an important health problem, disease is driven by allergen-specific Th2 immune responses. Differentiation of Th2 cells depends on their early interactions with antigen presenting cells, such as dendritic cells (DCs), and cytokines are crucial for this process. Osteopontin (Opn) was originally identified as an important cytokine for Th1 immunity and autoimmunity. Our group recen ...
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 2

 TERMINÉ 

Access to cultural heritage networks for Europeana (AthenaPlus)

Date du début: 1 mars 2013, Date de fin: 31 oct. 2015,

AthenaPlus will build on the successful experience developed by the previous ATHENA project – where LIDO and the ATHENA Ingestion Server and Mapping Tool (MINT), widely used across the Europeana's ecosystem of projects including the ongoing Linked Heritage project were developed, in order to further advance and complete the effective infrastructure and tools developed to support museums and other ...
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 41

 TERMINÉ 

Modulating motor output in the mammalian spinal cord (MODULATIONSPINALCORD)

Date du début: 1 sept. 2011, Date de fin: 31 août 2015,

The executive component of movement – the task of determining which muscles to activate, how intensely, and for how long – depends on neural circuits located in the spinal cord. At the core of these circuits are local interneurons (INTs) that regulate the pattern and frequency of motor neuron (MN) firing. Spinal motor activity is shaped by a combination of amino acid mediated excitation and inhibi ...
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 2